Palken M
Birth Defects Orig Artic Ser. 1977;13(5):373-84.
Representative case reports of children subjected to ureteroplasty in the management of reflux have been presented. Five- to 12-year follow-up studies were analyzed with reference to renal growth and pyelonephritic changes; the effect of the degree of preoperative reflux was recorded. The following conclusions appear warranted: 1. Severity of reflux is a major factor determining renal status; the more marked the reflux, the greater the frequency and extent of CPN. 2. Kidneys which appear normal initially usually remain so;however, CPN may develop, sometimes to a severe degree (Fig. 9). 3. The growth potential of pyelonephritic kidneys is quite variable and not readily predictable (Fig. 9). 4. Prolonged exposure to reflux appears to be an unfavourable situation possibly accelerating renal deterioration.
已呈现了接受输尿管成形术治疗反流的儿童的代表性病例报告。对5至12年的随访研究进行了分析，涉及肾脏生长和肾盂肾炎变化；记录了术前反流程度的影响。以下结论似乎是合理的：1. 反流的严重程度是决定肾脏状况的主要因素；反流越明显，慢性肾盂肾炎（CPN）的发生频率和范围就越大。2. 最初看似正常的肾脏通常会保持正常；然而，CPN可能会发展，有时会发展到严重程度（图9）。3. 肾盂肾炎肾脏的生长潜力差异很大，难以预测（图9）。4. 长期暴露于反流似乎是一种不利情况，可能会加速肾脏恶化。
