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[大鼠脑不同部位的磷脂代谢与其中循环障碍程度之间的关系(颈动脉结扎后)]

[Relationship between the phospholipid metabolism of different portions of rat brain and the degree of circulatory disruption in them (following carotid artery ligation)].

作者信息

Gasteva S V, Zamuruev O N

出版信息

Biull Eksp Biol Med. 1977 Nov;84(11):539-41.

PMID:588727
Abstract

Bilateral ligation of common carotid arteries in rats caused a considerable reduction of the blood supply and also a marked fall of phospholipids (PL) metabolism in the hemispheres; in the diencephalon and the midbrain it occurred to a lesser degree; there were no alterations in the blood supply or the PL metabolism in the medulla oblongata and the cerebellum. Dependence of the extent of depression of the PL metabolism on the degree of blood supply disturbances varied in different brain regions. Even 5 hours after the ligation of both carotid arteries there was no restoration of blood supply.

摘要

大鼠双侧颈总动脉结扎导致血液供应显著减少,同时大脑半球磷脂(PL)代谢明显下降;间脑和中脑的下降程度较小;延髓和小脑的血液供应及PL代谢无变化。不同脑区PL代谢抑制程度对血液供应紊乱程度的依赖性各不相同。即使在双侧颈动脉结扎5小时后,血液供应仍未恢复。

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