关于患腮腺炎、水痘、麻疹儿童及麻疹疫苗接种的染色体研究

Chun T, Alexander D S, Bryans A M, Haust M D

Can Med Assoc J. 1966 Jan 15;94(3):126-9.

A study to assess chromosomal damage in persons with acute viral diseases was undertaken in view of conflicting reports in the literature concerning such damage. Forty children with measles, mumps, and chickenpox, or who had received measles vaccine, were investigated and compared with a control group of 12 children. No greater incidence of chromosomal abnormalities was found in the study group than in the control group.

鉴于文献中关于急性病毒性疾病患者染色体损伤的报道相互矛盾，开展了一项评估此类患者染色体损伤情况的研究。对40名患有麻疹、腮腺炎、水痘或接种过麻疹疫苗的儿童进行了调查，并与12名儿童组成的对照组进行了比较。研究组中染色体异常的发生率并不高于对照组。