Sereny G, Fryatt M
Can Med Assoc J. 1966 Jan 1;94(1):8-12.
The records of 95 chronic alcoholic patients first admitted to the Addiction Research Foundation hospital, Toronto, in 1962 were examined; in 63 of these sufficient follow-up information was available for six months after hospitalization to permit further study.It was found that the prescription of tranquillizers or deterrent drugs could be related only to the individual physician's inclination toward drug therapy. Significantly more female than male patients received antidepressants and proportionately more females than males were found in the 41-50 year age group, suggesting a possible connection between menopausal age, onset of depressive symptoms, and uncontrolled drinking. No correlation was found between relative degree of sobriety and the consumption of tranquillizers or deterrent drugs, the number of follow-up interviews, or regular psychotherapy. The mean age of the totally abstinent patients was significantly higher than that of the whole group, suggesting a connection between ageing and a decline in addiction to alcohol.
对1962年首次入住多伦多成瘾研究基金会医院的95名慢性酒精中毒患者的记录进行了检查；其中63名患者在住院后六个月有足够的随访信息，可供进一步研究。结果发现，镇静剂或威慑药物的处方仅与个体医生对药物治疗的倾向有关。接受抗抑郁药治疗的女性患者明显多于男性患者，且在41 - 50岁年龄组中女性比例相对高于男性，这表明更年期年龄、抑郁症状发作与无节制饮酒之间可能存在联系。未发现清醒程度与镇静剂或威慑药物的使用、随访访谈次数或定期心理治疗之间存在相关性。完全戒酒患者的平均年龄明显高于整个研究组，这表明衰老与酒精成瘾性下降之间存在联系。
