Zayed S, Hafez A, Adolf W, Hecker E
Experientia. 1977 Dec 15;33(12):1554-5. doi: 10.1007/BF01933991.
From the methanol extract of Pimelea prostrata, prostratin (I) and 2 autoxidation products have been isolated. They are tigliane derivatives and relatively nonirritant on the mouse ear. The irritant pimelea factor P5 (IIa) also with a tigliane skeleton and related to mancinellin (IIb), as well as the irritant diterpene ester pimelea factor P1 (IIa, simplexin) with daphnane skeleton, were found to be present in both P. prostrata and P. simplex. Further the irritant homologue of simplexin, pimela factor IIIb was detected in P. prostrata. Some biogenetic consequences of these findings are discussed.
从平卧银桦的甲醇提取物中分离出了原卫矛醇（I）和2种自氧化产物。它们是大戟烷衍生物，对小鼠耳部相对无刺激性。具有大戟烷骨架且与毒番石榴素（IIb）相关的刺激性银桦因子P5（IIa），以及具有瑞香烷骨架的刺激性二萜酯银桦因子P1（IIa，单辛素），在平卧银桦和单花银桦中均被发现。此外，在平卧银桦中还检测到了单辛素的刺激性同系物银桦因子IIIb。讨论了这些发现的一些生源学结果。
