大鼠中过敏抗体从母体向幼体的转移。
Transfer of anaphylactic antibodies from mother to young in the rat.
作者信息
Perrudet-Badoux A, Binaghi R A
出版信息
Immunology. 1977 Dec;33(6):881-5.
The transfer of anaphylactic antibodies of classes IgE and IgGa from immunized female rats to babies was examined during primary and secondary immunization by injection, and also in rats infested with Trichinella spiralis. IgE antibodies were never detected in the blood of the babies, although they were sometimes detected in the milk in their stomachs. Similarly, no IgE antibodies were found in the serum of babies from mothers infested with Trichinella spiralis during pregnancy. IgGa antibodies were present in the serum and milk of the mothers following secondary immunization, and were readily absorbed through the intestine of the babies.
在初次和二次免疫期间，通过注射对免疫后的雌性大鼠向幼鼠转移IgE和IgGa类过敏抗体进行了检测，同时也对感染旋毛虫的大鼠进行了检测。尽管有时在幼鼠胃内的乳汁中检测到IgE抗体，但在幼鼠血液中从未检测到。同样，在孕期感染旋毛虫的母亲所生幼鼠的血清中也未发现IgE抗体。二次免疫后，母亲的血清和乳汁中存在IgGa抗体，并且很容易被幼鼠肠道吸收。
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