Friedrich B, Klaue P
Injury. 1977 Aug;9(1):23-9. doi: 10.1016/0020-1383(77)90045-6.
Stable and unstable internal fixation of fractures was performed in rabbits. After inoculation with Staphylococcus aureus, clinically manifest osteitis occurred only in the very unstable fractures. Abscesses, sinuses and sequestra developed in 45 per cent of the unstable fractures, whereas clinically manifest osteitis did not occur after rigid fixation. With rigid fixation there was no significant difference in the time to bony union between the infected and uninfected fractures. It seems that the development of osteitis and the healing of a fracture are both related to the degree of rigidity, but remain independent of each other. The significance of these findings in the management of posttraumatic osteitis is discussed.
对兔子进行骨折的稳定和不稳定内固定。接种金黄色葡萄球菌后，仅在极不稳定的骨折中出现临床明显的骨炎。45%的不稳定骨折出现脓肿、窦道和死骨，而坚强固定后未出现临床明显的骨炎。坚强固定时，感染骨折与未感染骨折在骨愈合时间上无显著差异。骨炎的发生和骨折的愈合似乎都与固定的牢固程度有关，但彼此独立。讨论了这些发现对创伤后骨炎治疗的意义。
