肾功能的血浆酚红排泄率指数（PSPI）：I. 理论思考与研究探讨。
The plasma phenolsulfonphthalein index (PSPI) of renal function: I. Theoretical considerations and investigative studies.
作者信息
Gault M H
出版信息
Can Med Assoc J. 1966 Jan 8;94(2):61-7.
Abstract
A simple method is described for the assessment of renal function, without collection of urine. Phenolsulfonphthalein (PSP) is injected intravenously in a dosage of 1 mg./kg. body weight, and blood samples are taken at timed intervals. Only one venepuncture is required. The index is based on the rate of decrease in concentration of PSP in the plasma 15 to 35 minutes after injection, during which time this rate is exponential. The methodology and normal range, and the influence of dose, urine flow rate, age and body surface are defined. The extrarenal component of the PSP index and the distribution of PSP in body fluids are discussed.
摘要
本文描述了一种无需收集尿液即可评估肾功能的简单方法。以每千克体重1毫克的剂量静脉注射酚红（PSP），并在规定的时间间隔采集血样。仅需进行一次静脉穿刺。该指标基于注射后15至35分钟血浆中PSP浓度的下降速率，在此期间该速率呈指数关系。定义了该方法、正常范围以及剂量、尿流率、年龄和体表面积的影响。讨论了PSP指数的肾外成分以及PSP在体液中的分布。
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The plasma phenolsulfonphthalein index (PSPI) of renal function: I. Theoretical considerations and investigative studies.肾功能的血浆酚红排泄率指数（PSPI）：I. 理论思考与研究探讨。
Can Med Assoc J. 1966 Jan 8;94(2):61-7.
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Am J Physiol. 1950 Mar;160(3):526-31. doi: 10.1152/ajplegacy.1950.160.3.526.
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