Vir S C, Love A H
Int J Vitam Nutr Res. 1977;47(4):336-44.
A combined dietary, biochemical and clinical study was carried out on 196 aged subjects residing at home and institutions (hospital, residential accommodation and sheltered dwelling) to evaluate the nutritional status of riboflavin and to assess the effect of regular vitamin supplementation. The dietary intake of vitamin B2 was below two-thirds of the recommended in 33.3 per cent males and 17l9 per cent females. Biochemical deficiency of riboflavin was noted in 7.1 per cent subjects by erythrocyte glutathione reductase (EGR) activity coefficient (AC) test. An association between activity coefficient and low intake was found when the coefficient was greater than or equal to 1.30. There was no significant correlation between activity coefficient and dietary vitamin B2/day or vitamin B2/100 g protein. Regular oral administration of multivitamin (containing 2.5 mg vitamin B2) prevented biochemical deficiency of the vitamin. Clinical signs of riboflavin deficiency were not seen except in one female subject of sheltered dwelling.
对196名居住在家中及机构(医院、住宿机构和庇护所)的老年人进行了一项饮食、生化和临床联合研究,以评估核黄素的营养状况,并评估定期补充维生素的效果。33.3%的男性和17/9%的女性维生素B2的饮食摄入量低于推荐量的三分之二。通过红细胞谷胱甘肽还原酶(EGR)活性系数(AC)测试,7.1%的受试者存在核黄素生化缺乏。当系数大于或等于1.30时,发现活性系数与低摄入量之间存在关联。活性系数与每日饮食维生素B2或维生素B2/100克蛋白质之间无显著相关性。定期口服多种维生素(含2.5毫克维生素B2)可预防该维生素的生化缺乏。除了一名居住在庇护所的女性受试者外,未观察到核黄素缺乏的临床体征。