Ruzbarský V, Michal V
Invest Urol. 1977 Nov;15(3):194-9.
The arterial vascular bed of the penis has been studied histologically in postmortem material from 30 males in the age range 19 to 85 years, mean 57. Fifteen of these propositi had had diabetes mellitus of average duration of 13 years. In all males more than 38 years old, there was fibrous substitution of the longitudinal smooth muscle in the Ebner pads. Later this was complemented by fibrous proliferation of the intima, medial fibrosis, calcification, and narrowing of the lumen to obilteration from thrombi. The extent of the pathology was apparently related to both age and diabetes mellitus. The nature and extent of the changes indicate that they must necessarily lead to a limitation of the basic function of this arterial tree, i.e., to increase essentially the flow of blood to the cavernous bodies at the time of the erection. These changes can play a decisive role in explaining impotence that occurs with aging, particularly in diabetics.
对年龄在19至85岁（平均57岁）的30名男性尸检材料中的阴茎动脉血管床进行了组织学研究。其中15名受试者患有平均病程为13年的糖尿病。在所有38岁以上的男性中，埃布纳垫的纵向平滑肌出现纤维性替代。随后，内膜纤维增生、中层纤维化、钙化以及管腔因血栓形成而狭窄至闭塞。病理变化的程度显然与年龄和糖尿病都有关。这些变化的性质和程度表明，它们必然会导致该动脉系统基本功能的受限，即在勃起时基本增加流向海绵体的血流量。这些变化在解释随年龄增长出现的阳痿，尤其是糖尿病患者的阳痿方面可能起决定性作用。
