Collins J F
Can Med Assoc J. 1966 Aug 6;95(6):270-2.
The causation of congenital malformation is receiving increased study. In Canada, epidemiologic surveys are being planned, based upon the institution of Provincial Registries to which physicians and other agencies will voluntarily report cases coming to their attention. The literature in regard to prevalence studies of congenital cardiac defects in school children is reviewed. Over the past 25 years, studies employing the proposed technique demonstrated a rising trend, from 1.4 per 1000 to 2.6 per 1000. By contrast, specific surveys for congenital cardiac defect carried out by expert personnel using radiographs and electrocardiographs, resulted in essentially uniform rates, approximating 5 to 6 per 1000. It is concluded that the latter is a superior technique of epidemiologic survey over the "Central Registry" method, and should command a due proportion of health resources directed towards congenital malformation research.
先天性畸形的病因正受到越来越多的研究。在加拿大，基于省级登记机构的设立正在计划进行流行病学调查，医生和其他机构将自愿向该机构报告他们所关注到的病例。本文回顾了关于学龄儿童先天性心脏缺陷患病率研究的文献。在过去25年中，采用所提议技术的研究显示出上升趋势，从每1000人中有1.4例升至每1000人中有2.6例。相比之下，由专业人员使用X光片和心电图对先天性心脏缺陷进行的专项调查，得出的发病率基本一致，约为每1000人中有5至6例。结论是，后一种方法是比“中央登记”方法更优越的流行病学调查技术，应在用于先天性畸形研究的卫生资源中占适当比例。
