Malone J F, Cullen M J
Lancet. 1976 Jul 10;2(7976):73-5. doi: 10.1016/s0140-6736(76)92290-x.
It is proposed that the incidence of hypothyroidism after radioiodine therapy of thyrotoxicosis has two distinct mechanism. One operates in the first two years after therapy and depends on radiation dose. The other operates in later years, and is not, to any significant extent, dose dependent. Possible canidates for each mechanism are explored.
有人提出,甲状腺毒症放射性碘治疗后甲状腺功能减退的发生率有两种不同机制。一种在治疗后的头两年起作用,且取决于辐射剂量。另一种在后期起作用,且在很大程度上与剂量无关。对每种机制的可能候选因素进行了探讨。