Falkner B, Langman C, Katz S
J Clin Pathol. 1977 Nov;30(11):1077-81. doi: 10.1136/jcp.30.11.1077.
This report describes a case of Laurence-Moon-Biedl syndrome identified in a 24-month-old boy. Significant renal involvement was present with right-sided vesicoureteral reflux, cystocele, urinary tract infections, and growth arrest of the right kidney. After the development of hypertension a left renal biopsy was performed to determine if bilateral renal disease was present. Histopathological and ultrastructural changes in the left kidney are described. These changes appear to be unrelated to pyelonephritis or hypertension and to be most consistent with the nephropathy of Laurence-Moon-Biedl syndrome.
本报告描述了一名24个月大男孩被诊断为劳伦斯-穆恩-比德尔综合征的病例。该患儿存在严重的肾脏受累情况，包括右侧膀胱输尿管反流、膀胱膨出、尿路感染以及右肾生长停滞。在出现高血压后，进行了左肾活检以确定是否存在双侧肾脏疾病。文中描述了左肾的组织病理学和超微结构变化。这些变化似乎与肾盂肾炎或高血压无关，最符合劳伦斯-穆恩-比德尔综合征的肾病表现。
