Krauel X, Berger R, Amiel-Tison C
J Genet Hum. 1977 Oct;25(3):205-14.
Two cases of cerebral gigantism occurring in related boys (cousins of 3rd degree) are discussed. It is difficult to argue from these cases in favour of a precise type of hereditary transmission. The hypothesis of a dominant trait with weak penetrance cannot be excluded. A genetic heterogeneity of the Sotos syndrome is very likely.
本文讨论了两例发生在相关男孩(三代堂兄弟)身上的脑性巨人症病例。很难从这些病例推断出一种精确的遗传传递类型。具有弱外显率的显性性状假说不能排除。索托斯综合征的遗传异质性很可能存在。