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Evaluation of the peripheral deiodination of L-thyroxine as an index of its thyrotrophin suppressing effectiveness.

作者信息

Mouriz J, Morreale de Escobar G, Escobar del Rey F

出版信息

Endocrinology. 1966 Aug;79(2):248-60. doi: 10.1210/endo-79-2-248.

DOI:10.1210/endo-79-2-248
PMID:5921765
Abstract
摘要

相似文献

1
Evaluation of the peripheral deiodination of L-thyroxine as an index of its thyrotrophin suppressing effectiveness.
Endocrinology. 1966 Aug;79(2):248-60. doi: 10.1210/endo-79-2-248.
2
Studies on deiodination occurring during pancreatin digestion of thyroid homogenates and its prevention by methimazole.关于甲状腺匀浆胰酶消化过程中发生的脱碘作用及其被甲巯咪唑预防的研究。
Endocrinology. 1966 Sep;79(3):601-7. doi: 10.1210/endo-79-3-601.
3
The effects of propylthiouracil, thyroxine, and hypophysectomy on the iodinating activity of the rat thyroid gland.
Can J Physiol Pharmacol. 1968 May;46(3):449-52. doi: 10.1139/y68-067.
4
Thyroidal radioiodine uptake and thyrotropic potency of the pituitary in a freshwater catfish, Mystus vittatus (Bloch), in response to L-thyroxin, antithyroid drugs, and heavy doses of 131-I.淡水鲶鱼（Mystus vittatus，布洛赫）对L-甲状腺素、抗甲状腺药物和大剂量131-I的甲状腺放射性碘摄取及垂体促甲状腺效能
Z Zellforsch Mikrosk Anat. 1969;94(2):172-80. doi: 10.1007/BF00339354.
5
Mechanism of goitorogenesis by very low doses of propylthiouracil and the role of iodine intake.
Acta Endocrinol (Copenh). 1968 Dec;59(4):529-44. doi: 10.1530/acta.0.0590529.
6
Some effects of actinomycin D on iodine metabolism in the rat thyroid.放线菌素D对大鼠甲状腺碘代谢的某些影响。
Endocrinology. 1966 Aug;79(2):424-31. doi: 10.1210/endo-79-2-424.
7
Thyrotropin secretion and metabolism in rats during propylthiouracil treatment.丙硫氧嘧啶治疗期间大鼠促甲状腺激素的分泌与代谢
Endocrinology. 1973 Jan;92(1):166-73. doi: 10.1210/endo-92-1-166.
8
Degradation of thyroxine by a thyroidal peroxidase.甲状腺过氧化物酶对甲状腺素的降解作用。
Endocrinology. 1971 Jan;88(1):144-8. doi: 10.1210/endo-88-1-144.
9
An in vitro bioassay for thyrotrophin (TSH).
Endocrinology. 1969 May;84(5):1286-91. doi: 10.1210/endo-84-5-1286.
10
Studies on the mechanism of the inhibitory action of excess iodide on the release of radioiodine from the rat thyroid gland.关于过量碘对大鼠甲状腺释放放射性碘抑制作用机制的研究。
Endocrinology. 1968 Jan;82(1):54-61. doi: 10.1210/endo-82-1-54.

引用本文的文献

1
Propylthiouracil inhibits the conversion of L-thyroxine to L-triiodothyronine. An explanation of the antithyroxine effect of propylthiouracil and evidence supporting the concept that triiodothyronine is the active thyroid hormone.丙硫氧嘧啶抑制L-甲状腺素转化为L-三碘甲状腺原氨酸。对丙硫氧嘧啶的抗甲状腺素作用的解释以及支持三碘甲状腺原氨酸是活性甲状腺激素这一概念的证据。
J Clin Invest. 1972 Sep;51(9):2493-7. doi: 10.1172/JCI107063.
2
Propylthiouracil blocks extrathyroidal conversion of thyroxine to triiodothyronine and augments thyrotropin secretion in man.丙硫氧嘧啶可阻断甲状腺外甲状腺素向三碘甲状腺原氨酸的转化，并增加人体促甲状腺素的分泌。
J Clin Invest. 1975 Feb;55(2):224-9. doi: 10.1172/JCI107925.
3
Thyrotropic activity of hypophysis in rats of different ages.
不同年龄大鼠垂体的促甲状腺活性
Neurosci Behav Physiol. 1979 Oct-Dec;9(4):366-9. doi: 10.1007/BF01185058.