Evaluation of the peripheral deiodination of L-thyroxine as an index of its thyrotrophin suppressing effectiveness.
作者信息
Mouriz J, Morreale de Escobar G, Escobar del Rey F
出版信息
Endocrinology. 1966 Aug;79(2):248-60. doi: 10.1210/endo-79-2-248.
PMID:5921765
Abstract
摘要
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Evaluation of the peripheral deiodination of L-thyroxine as an index of its thyrotrophin suppressing effectiveness.
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引用本文的文献
1
Propylthiouracil inhibits the conversion of L-thyroxine to L-triiodothyronine. An explanation of the antithyroxine effect of propylthiouracil and evidence supporting the concept that triiodothyronine is the active thyroid hormone.丙硫氧嘧啶抑制L-甲状腺素转化为L-三碘甲状腺原氨酸。对丙硫氧嘧啶的抗甲状腺素作用的解释以及支持三碘甲状腺原氨酸是活性甲状腺激素这一概念的证据。
J Clin Invest. 1972 Sep;51(9):2493-7. doi: 10.1172/JCI107063.
2
Propylthiouracil blocks extrathyroidal conversion of thyroxine to triiodothyronine and augments thyrotropin secretion in man.丙硫氧嘧啶可阻断甲状腺外甲状腺素向三碘甲状腺原氨酸的转化，并增加人体促甲状腺素的分泌。
J Clin Invest. 1975 Feb;55(2):224-9. doi: 10.1172/JCI107925.
3
Thyrotropic activity of hypophysis in rats of different ages.不同年龄大鼠垂体的促甲状腺活性
Neurosci Behav Physiol. 1979 Oct-Dec;9(4):366-9. doi: 10.1007/BF01185058.
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