Gordon P C
Can Med Assoc J. 1966 Nov 12;95(20):1004-11.
Mortality data for cerebral vascular disease in Canada and its provinces were analysed as an initial approach to the understanding of the epidemiology of this disease. Since 1950, there has been a decline in mortality attributed to vascular lesions of the central nervous system. This decline has been more pronounced in females. Five-year average age-sex-specific rates (1960-64) showed an almost constant proportional increase with age. The highest mortality rates tended to occur in the Eastern Provinces.From 1950 to 1964 there was a 21% decline in mortality due to intracranial hemorrhage and a concomitant 53% decline in mortality attributed to hypertensive disease. Over the same period there was a 24% increase in mortality attributed to cerebral embolism and thrombosis, and an 8% increase in mortality due to arteriosclerotic heart disease. Areal correlations offered only inconsistent support for the hypothesis that these associated trends are due to common etiologic determinants.Evidence presently available does little to clarify to what extent these trends and differences can be attributed to coding, certification and diagnostic practices, and to what extent to changing and differing incidence and prognosis.
对加拿大及其各省的脑血管疾病死亡率数据进行了分析,以此作为初步了解该疾病流行病学的方法。自1950年以来,归因于中枢神经系统血管病变的死亡率有所下降。这种下降在女性中更为明显。1960 - 1964年的五年平均年龄别死亡率显示,死亡率几乎随年龄呈恒定的比例上升。最高死亡率往往出现在东部省份。1950年至1964年,颅内出血导致的死亡率下降了21%,同时高血压疾病导致的死亡率下降了53%。在同一时期,脑栓塞和血栓形成导致的死亡率上升了24%,动脉硬化性心脏病导致的死亡率上升了8%。区域相关性仅为这些相关趋势归因于共同病因决定因素这一假说提供了不一致的支持。目前可得的证据几乎无法阐明这些趋势和差异在多大程度上可归因于编码、认证和诊断实践,以及在多大程度上可归因于发病率和预后的变化及差异。