Lobova T M, Chernyĭ A V
Kosm Biol Aviakosm Med. 1977 Nov-Dec;11(6):36-40.
Experiments on 140 white rats kept under hypokinetic conditions for 15, 30, 60 and 90 days showed a significant decrease of the glycogen content in the liver and skeletal muscles, acceleration of lipolysis in the adipose tissue, progressive increase of the content of nonesterified fatty acids, ketone bodies and cholesterol in the blood, decrease of the content of total lipids and increase of the cholesterol content in the skeletal muscles and liver. Hypokinetic rats exposed to exercises (swimming) also exhibited changes in carbohydrate and lipid metabolism; however the content of ketone bodies in the blood increased a little, the glycogen content in tissues decreased to a lesser extent, the cholesterol level in the and skeletal muscles increased only on the 15th day, remained at the control level at later stages and even decreased in the skeletal muscles. Thus, during an exposure to hypokinesia and its combination with exercises the role of lipids on the energy balance of the animal body increases. Exercises facilitate better utilization of lipids, thus delaying adverse effects of hypokinesia.
对140只在低动力条件下分别饲养15天、30天、60天和90天的白鼠进行的实验表明，肝脏和骨骼肌中的糖原含量显著降低，脂肪组织中的脂肪分解加速，血液中游离脂肪酸、酮体和胆固醇的含量逐渐增加，骨骼肌和肝脏中的总脂质含量降低，胆固醇含量增加。进行运动（游泳）的低动力白鼠在碳水化合物和脂质代谢方面也出现了变化；然而，血液中的酮体含量略有增加，组织中的糖原含量下降幅度较小，肝脏和骨骼肌中的胆固醇水平仅在第15天有所增加，在后期保持在对照水平，甚至在骨骼肌中有所下降。因此，在低动力状态及其与运动相结合的情况下，脂质在动物体能量平衡中的作用增强。运动有助于更好地利用脂质，从而延缓低动力状态的不利影响。
