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[Carbohydrate metabolism during poisoning with the cholinesterase inhibitor O-ethyl-S-hexylmethylthiophosphonate].

作者信息

Rozengart V I, Chetverikova E K, Mozgovaia I A

出版信息

Vopr Med Khim. 1971 Jul-Aug;17(4):403-7.

PMID:5317625
Abstract

It is established that a decrease in glycogen content in liver begins at the early stages of intoxication with LG-63 and progresses with development of intoxication phenomena. Sugar content in liver and blood augments in parallel with decreasing content of glycogen in liver; concentration of ketone bodies and content of bisulfite-binding substances and pyruvic acid in liver also increase. In skeletal muscles, glycogen content was practically without changes; content of sugar, bisulfite-binding substances and pyruvic acid decreased while level of ketone bodies increased. In brain, utilization of ketone bodies decreased and in myocardium, increased.

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