[Carbohydrate metabolism during poisoning with the cholinesterase inhibitor O-ethyl-S-hexylmethylthiophosphonate].

It is established that a decrease in glycogen content in liver begins at the early stages of intoxication with LG-63 and progresses with development of intoxication phenomena. Sugar content in liver and blood augments in parallel with decreasing content of glycogen in liver; concentration of ketone bodies and content of bisulfite-binding substances and pyruvic acid in liver also increase. In skeletal muscles, glycogen content was practically without changes; content of sugar, bisulfite-binding substances and pyruvic acid decreased while level of ketone bodies increased. In brain, utilization of ketone bodies decreased and in myocardium, increased.