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[不同个体放射敏感性动物下丘脑-垂体-肾上腺系统活动的每日变化]

[Daily changes in the activity of the hypothalamus-hypophysis-adrenal system in animals with varying individual radiosensitivity].

作者信息

Druzhinin Iu P, Zubkova-Mikhaĭlova E I, Podluzhnaia G N

出版信息

Kosm Biol Aviakosm Med. 1977 Nov-Dec;11(6):40-5.

PMID:592709
Abstract

Circadian variations in the functional activity of the hypothalamic-pituitary-adrenal (HPA) system of Wistar rats with different individual radiosensitivity were studied. The latter was measured using an adrenaline test. The rats that differed in their radiosensitivity showed dissimilar circadian changes which included the amplitude, position of acrophases, pattern of periodic processes in the HPA system. Radioresistant rats exhibited a smaller amplitude of changes in the HPA system and a significantly larger amplitude of variations of the effectors.

摘要

研究了具有不同个体放射敏感性的Wistar大鼠下丘脑 - 垂体 - 肾上腺(HPA)系统功能活动的昼夜变化。后者通过肾上腺素试验进行测量。放射敏感性不同的大鼠表现出不同的昼夜变化,包括HPA系统变化的幅度、高峰相位位置、周期性过程模式。抗辐射大鼠的HPA系统变化幅度较小,而效应器的变化幅度明显较大。

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