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1
Possible use of phosphohexose isomerase as a preliminary to exfoliative cytology in screening for cervical carcinoma.磷酸己糖异构酶在宫颈癌筛查中作为脱落细胞学检查的初步手段的可能应用。
J Clin Pathol. 1966 Jul;19(4):378-83. doi: 10.1136/jcp.19.4.378.
2
Vaginal fluid enzyme patterns in benign and malignant lesions of the female genital tract.女性生殖道良性和恶性病变中的阴道液酶谱
J Clin Pathol. 1969 Sep;22(5):593-7. doi: 10.1136/jcp.22.5.593.
3
A trial of phosphohexose isomerase as a means of detecting cervical carcinoma.磷酸己糖异构酶作为检测宫颈癌手段的一项试验。
J Clin Pathol. 1968 Jan;21(1):24-6. doi: 10.1136/jcp.21.1.24.
4
Technical modifications of the 6-phosphogluconate dehydrogenase test of the vaginal fluid.阴道分泌物6-磷酸葡萄糖酸脱氢酶试验的技术改进
Am J Obstet Gynecol. 1967 Jul 15;98(6):800-3. doi: 10.1016/0002-9378(67)90196-2.
5
Diagnostic and prognostic significance of serum phosphohexose isomerase, aldolase and hexokinase in carcinoma cervix.血清磷酸己糖异构酶、醛缩酶和己糖激酶在宫颈癌中的诊断及预后意义
Indian J Physiol Pharmacol. 1986 Apr-Jun;30(2):177-81.
6
Exfoliative cytology of the uterine cervix and vagina.子宫颈和阴道的脱落细胞学检查
CA Cancer J Clin. 1960 Nov-Dec;10:182-93. doi: 10.3322/canjclin.10.6.182.
7
The source of 6-phosphogluconate dehydrogenase in vaginal fluid samples.阴道液样本中6-磷酸葡萄糖酸脱氢酶的来源。
J Obstet Gynaecol Br Commonw. 1967 Oct;74(5):712-22. doi: 10.1111/j.1471-0528.1967.tb03785.x.
8
The early diagnosis of carcinoma of the female genital tract. II. Vaginal fluid 6-phosphogluconate dehydrogenase activity as a test for carcinoma of the cervix.女性生殖道癌的早期诊断。二、阴道液6-磷酸葡萄糖酸脱氢酶活性作为宫颈癌的一项检测指标
J Obstet Gynaecol Br Commonw. 1965 Oct;72(5):684-90.
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False negative rate in cervical cytology.宫颈细胞学检查中的假阴性率。
J Clin Pathol. 1987 Apr;40(4):438-42. doi: 10.1136/jcp.40.4.438.
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Exfoliative cytology in the early detection of cervical carcinoma in General Practice.全科医疗中宫颈癌细胞学检查在宫颈癌早期检测中的应用
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引用本文的文献

1
Vaginal fluid enzyme patterns in benign and malignant lesions of the female genital tract.女性生殖道良性和恶性病变中的阴道液酶谱
J Clin Pathol. 1969 Sep;22(5):593-7. doi: 10.1136/jcp.22.5.593.

本文引用的文献

1
A well-women's clinic.妇女健康诊所。
Lancet. 1962 Aug 25;2(7252):395-6. doi: 10.1016/s0140-6736(62)90247-7.
2
Serum glycolytic enzymes and acid phosphatases in mammary carcinomatosis.乳腺癌转移患者血清中的糖酵解酶和酸性磷酸酶
Br Med J. 1962 Mar 24;1(5281):827-31. doi: 10.1136/bmj.1.5281.827.
3
Vaginal fluid beta-glucuronidase--with special reference to cancer of the cervix.阴道液β-葡萄糖醛酸酶——特别提及宫颈癌
J Obstet Gynaecol Br Emp. 1959 Dec;66:946-53. doi: 10.1111/j.1471-0528.1959.tb01965.x.
4
6-PHOSPHOGLUCONATE DEHYDROGENASE ESTIMATION IN VAGINAL FLUID IN THE DIAGNOSIS OF CERVICAL CANCER.阴道液中6-磷酸葡萄糖酸脱氢酶测定在宫颈癌诊断中的应用
J Obstet Gynaecol Br Commonw. 1965 Aug;72:603-9. doi: 10.1111/j.1471-0528.1965.tb00070.x.
5
LEVELS OF PHOSPHOHEXOSE ISOMERASE IN CARCINOMATOUS BREAST TISSUE IN RELATION TO HISTOLOGICAL GRADING.癌性乳腺组织中磷酸己糖异构酶水平与组织学分级的关系
Br J Cancer. 1965 Jun;19(2):274-7. doi: 10.1038/bjc.1965.31.
6
USE OF 6-PHOSPHOGLUCONATE DEHYDROGENASE AS A SCREEN TEST FOR CERVICAL CARCINOMA IN NORMAL WOMEN.6-磷酸葡萄糖酸脱氢酶作为正常女性宫颈癌筛查试验的应用
Br Med J. 1964 Dec 19;2(5424):1563-5. doi: 10.1136/bmj.2.5424.1563.
7
SOME GROWTH, MORPHOLOGICAL AND BIOCHEMICAL CHARACTERISTICS OF HEPATOMA 5123 AND OTHER NEW TRANSPLANTABLE HEPATOMAS.肝癌5123及其他新的可移植性肝癌的一些生长、形态学和生物化学特征
Prog Exp Tumor Res. 1963;3:370-411. doi: 10.1159/000385968.
8
A new enzyme test for gynaecological cancer. 6-Phosphogluconate dehydrogenase activity in vaginal fluid.一种用于妇科癌症的新型酶检测。阴道液中的6-磷酸葡萄糖酸脱氢酶活性。
Br Med J. 1962 Sep 29;2(5308):823-4. doi: 10.1136/bmj.2.5308.823.
9
Glucose-6-phosphate utilization in hepatoma, regenerating and newborn rat liver, and in the liver of fed and fasted normal rats.肝癌、再生肝和新生大鼠肝脏以及正常喂食和禁食大鼠肝脏中葡萄糖-6-磷酸的利用情况。
Cancer Res. 1957 Nov;17(10):995-1005.
10
Serum phosphohexose isomerase in cancer. I. Method of determination and establishment of range of normal values.癌症中的血清磷酸己糖异构酶。I. 测定方法及正常数值范围的确立。
Cancer. 1954 Nov;7(6):1191-9. doi: 10.1002/1097-0142(195411)7:6<1191::aid-cncr2820070611>3.0.co;2-3.

磷酸己糖异构酶在宫颈癌筛查中作为脱落细胞学检查的初步手段的可能应用。

Possible use of phosphohexose isomerase as a preliminary to exfoliative cytology in screening for cervical carcinoma.

作者信息

Muir G G

出版信息

J Clin Pathol. 1966 Jul;19(4):378-83. doi: 10.1136/jcp.19.4.378.

DOI:10.1136/jcp.19.4.378
PMID:5929340
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC473288/
Abstract

The activities of phosphohexose isomerase and 6-phosphogluconate dehydrogenase have been studied in the vaginal fluid of women from the gynaecological departments. Women from these departments gave a very high false positive rate, though no cases of carcinoma in situ were not detected by estimating phosphohexose isomerase levels. It gave considerably better results in malignancy than 6-phosphogluconate dehydrogenase. It is suggested that the use of phosphohexose isomerase might be of value in screening well women during a mass cytology programme.

摘要

已对妇科门诊女性阴道分泌物中的磷酸己糖异构酶和6 - 磷酸葡萄糖酸脱氢酶的活性进行了研究。这些科室的女性假阳性率非常高，不过通过估计磷酸己糖异构酶水平未漏诊原位癌病例。在恶性肿瘤检测方面，它比6 - 磷酸葡萄糖酸脱氢酶的效果要好得多。有人提出，在大规模细胞学检查项目中，使用磷酸己糖异构酶可能对健康女性的筛查有价值。