Simon B, Kather H
Leber Magen Darm. 1977 Dec;7(6):383-5.
Human gastric mucosa contains a histamin-sensitive adenylate cyclase system. The activation of this enzyme system by histamine is competititively inhibited by the H2-receptor blocking agent cimetidine. Our results underscore the rational basis for the use 0f H2-receptor antagonists in the therapy of peptic ulcer.
人胃黏膜含有一种对组胺敏感的腺苷酸环化酶系统。组胺对该酶系统的激活受到H2受体阻断剂西咪替丁的竞争性抑制。我们的结果强调了使用H2受体拮抗剂治疗消化性溃疡的合理依据。
