在使用抗组胺药的情况下，未能证明亚致死性过敏反应后存在不应期。
Failure to demonstrate a refractory period following sublethal anaphylaxis under cover of antihistamine.
作者信息
Murphy C D, McDuffie F C
出版信息
Immunology. 1966 Jan;10(1):9-20.
Abstract
Attempts were made to desensitize guinea-pigs (which had been actively sensitized to bovine serum albumin) by injecting them 2 days before challenge with a near-lethal dose of the antigen under protection of antihistamine. No statistically significant desensitization occurred although there was a significant drop in the mean serum antibody titre as well as in the mean complement levels. However, antibody titre and sensitivity to anaphylaxis could not be correlated.
摘要
有人尝试对豚鼠（已对牛血清白蛋白产生主动致敏）进行脱敏处理，方法是在激发前2天，在组胺拮抗剂的保护下给它们注射接近致死剂量的抗原。尽管平均血清抗体滴度以及平均补体水平显著下降，但未出现具有统计学意义的脱敏现象。然而，抗体滴度与过敏反应敏感性之间并无关联。
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The adsorption of proteins on erythrocytes treated with tannic acid and subsequent hemagglutination by antiprotein sera.蛋白质在经单宁酸处理的红细胞上的吸附以及随后抗蛋白质血清引起的血细胞凝集。
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The production of skin-sensitizing antibody in the guinea-pig.豚鼠皮肤致敏抗体的产生。
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Drugs that modify actions of pharmacologically active polypeptides.改变药理活性多肽作用的药物。
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Properties of guinea pig 7S antibodies. III. Identification of antibodies involved in complement fixation and hemolysis.豚鼠7S抗体的特性。III. 补体结合和溶血相关抗体的鉴定。
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Properties of guinea pig 7S antibodies. I. Electrophoretic separation of two types of guinea pig 7S antibodies.豚鼠7S抗体的特性。I. 两种类型豚鼠7S抗体的电泳分离
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The mechanism of protection from anaphylactic shock in the guinea-pig by pre-treatment with anaphylatoxin.用过敏毒素预处理豚鼠预防过敏性休克的机制。
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