Cobble R S, Lynd F T
Mod Vet Pract. 1977 Dec;58(12):1009-12.
In 2 clinical studies of canine cataract, mostly bilateral, intraocular injection of orgotein (Palosein: Diagnostic Data) was followed by varying degrees of clearing of lens opacity and return of functional vision in 39 of 56 dogs, most of which were given 1 injection (1.25 mg). First evidence of sight return and lens clearing was observed at 3-14 weeks post-treatment. In 2 dogs, clearing of cataract was followed by recurrence, and repeat treatment in one of these effected improvement. Although these results must be considered preliminary, in part because they relate to clinical cases not susceptible to controlled study, the apparent success rate suggests the feasibility of larger-scale studies under controlled conditions.
在两项犬类白内障临床研究中（大多为双侧白内障），对56只犬中的39只进行眼内注射奥古蛋白（帕洛新：诊断数据公司）后，晶状体混浊出现不同程度的消退，并且恢复了功能性视力，其中大多数犬只接受了1次注射（1.25毫克）。治疗后3至14周观察到视力恢复和晶状体混浊消退的首个迹象。在2只犬中，白内障消退后又复发，其中1只犬重复治疗后病情有所改善。尽管这些结果必须视为初步结果，部分原因是它们涉及不易进行对照研究的临床病例，但明显的成功率表明在可控条件下进行更大规模研究的可行性。
