Clark L C, Gollan F
Science. 1966 Jun 24;152(3730):1755-6. doi: 10.1126/science.152.3730.1755.
Because oxygen and carbon dioxide are very soluble in certain silicone oils and fluorocarbon liquids, these liquids will support respiration of mammals. Mice and cats respiring silicone oil die shortly after return to air breathing, while those breathing fluorocarbon survive for weeks. The respiration of mice is optimally supported by these organic liquids at about 20 degrees C. In cats, arterial oxygenation is excellent, but there is some impairment of carbon dioxide elimination. All animals have suffered some pulmonary damage from breathing fluorocarbon liquids. Continued investigation of organic fluid respiration may lead to development of a safe method to support the respiration of man by liquids equilibrated with gases at atmospheric pressure.
由于氧气和二氧化碳在某些硅油和碳氟化合物液体中具有很高的溶解性，这些液体能够维持哺乳动物的呼吸。呼吸硅油的小鼠和猫在恢复空气呼吸后不久便会死亡，而呼吸碳氟化合物的小鼠和猫则能存活数周。在大约20摄氏度时，这些有机液体对小鼠呼吸的支持效果最佳。对于猫来说，动脉氧合情况良好，但二氧化碳的排出存在一定障碍。所有动物在呼吸碳氟化合物液体后都受到了一定程度的肺部损伤。对有机液体呼吸的持续研究可能会促成一种安全方法的开发，即通过在大气压下与气体平衡的液体来维持人类的呼吸。
