Boisson D, Annat G, Aimard G, Pequignot J N, Grivet B, Devic M
Nouv Presse Med. 1977 Dec 3;6(41):3839-41.
The authors report a case of grave orthostatic hypotension (Shy-Drager's syndrome) with major postural disturbances. The biological test confirmed a catecholaminergic deficiency. After several drugs were tried unsucessfully, an association of L-Dopa and fractionated doses of mono-amine-oxydase inhibitor was proposed. The increase blood pressure was sufficient to block the diturbances of postural adaptation, without inducing hypertensive jerks. The functionnal result have been stable for three years, while the parkinsonian syndrome have shown little progression.
作者报告了一例伴有严重姿势障碍的严重直立性低血压（夏伊-德雷格综合征）病例。生物学检测证实存在儿茶酚胺能缺乏。在尝试多种药物均未成功后，提出左旋多巴与分次剂量的单胺氧化酶抑制剂联合使用。血压升高足以阻止姿势适应障碍，且未引发高血压性抽搐。功能结果在三年来一直稳定，而帕金森综合征进展甚微。
