Potential biologically active agents. X. Synthesis of 3-arylimino-2-indolinones, and their 1-methyl- and 1-morpholino/piperidinomethyl derivatives as excystment and cysticidal agents against Schizopyrenus russelli.

Isatin and N -methylisatin have been condensed with alkylaminobenzoates to furnish 3-arylimino-2-indolinones and 1-methyl-3-arylimino-2-indolinones respectively. 3-Arylimino-2-indolinones were then subjected to Mannich reaction conditions to yield 1-morpholino/piperidinomethyl-3-arylimino-2-indolinones. The compounds thus synthesised were evaluated for their ability to cause excystment and cysticidal activity against Schizopyrenus russelli.