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Studies on methylazoxymethanol, the aglycone of cycasin: methylation of nucleic acids in vitro.

作者信息

Matsumoto H, Higa H H

出版信息

Biochem J. 1966 Feb;98(2):20C-22C. doi: 10.1042/bj0980020c.

DOI:10.1042/bj0980020c
PMID:5941330
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1264889/
Abstract
摘要

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Studies on methylazoxymethanol, the aglycone of cycasin: methylation of nucleic acids in vitro.关于苏铁苷元甲基偶氮甲醇的研究：体外核酸的甲基化作用
Biochem J. 1966 Feb;98(2):20C-22C. doi: 10.1042/bj0980020c.
2
Similarities between the biochemical actions of cycasin and dimethylnitrosamine.苏铁素与二甲基亚硝胺生化作用之间的相似性。
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3
The effects of methylation on the chemical and submicroscopic structure of tissue nuclei (DNA).甲基化对组织细胞核（DNA）的化学及亚微观结构的影响。
Acta Biol Acad Sci Hung. 1965;16(2):113-23.
4
STUDIES ON METHYLAZOXYMETHANOL, THE AGLYCONE OF CYCASIN: A SYNTHESIS OF METHYLAZOXYMETHYL ACETATE.苏铁苷配基甲基偶氮甲醇的研究：乙酸甲基偶氮甲氧基甲酯的合成
Biochem J. 1965 May;95:13C-14C. doi: 10.1042/bj0950013c.
5
METHYLAZOXYMETHANOL, THE AGLYCONE OF CYCASIN.甲基偶氮甲醇，苏铁苷的苷元。
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STUDIES ON METHYLAZOXYMETHANOL, THE AGLYCONE OF CYCASIN. ISOLATION, BIOLOGICAL, AND CHEMICAL PROPERTIES.苏铁苷元甲基氧化甲醇的研究。分离、生物学及化学性质。
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Mutagenicity of cycasin aglycone (methylazoxymethanol), a naturally occurring carcinogen.天然致癌物苏铁素苷元（甲基氧化偶氮甲醇）的致突变性。
Science. 1966 May 27;152(3726):1273-4. doi: 10.1126/science.152.3726.1273.
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[Natural carcinogens: aglycon-methylazoxymethanol in cycasin].[天然致癌物：苏铁素中的苷元-甲基偶氮甲醇]
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本文引用的文献

1
Occurrence of 5-methylcytosine in nucleic acids.核酸中5-甲基胞嘧啶的存在情况。
Nature. 1950 Aug 5;166(4214):237-8. doi: 10.1038/166237b0.
2
Chromatographic studies of nucleic acids; a technique for the identification and estimation of purine and pyrimidine bases, nucleosides and related substances.核酸的色谱研究；一种用于嘌呤和嘧啶碱基、核苷及相关物质的鉴定和定量的技术。
Biochem J. 1949;45(3):294-8. doi: 10.1042/bj0450294.
3
The composition of the deoxyribonucleic acid of salmon sperm.鲑鱼精子脱氧核糖核酸的组成
J Biol Chem. 1951 Sep;192(1):223-30.
4
The purine and pyrimidine composition of deoxypentose nucleic acids.脱氧戊糖核酸的嘌呤和嘧啶组成。
Biochem J. 1951 May;48(5):584-90. doi: 10.1042/bj0480584.
5
Toxic liver injury and carcinogenesis. Methylation of proteins of rat-liver slices by dimethylnitrosamine in vitro.中毒性肝损伤与致癌作用。二甲基亚硝胺在体外对大鼠肝切片蛋白质的甲基化作用。
Biochem J. 1962 Apr;83(1):106-14. doi: 10.1042/bj0830106.
6
Toxic liver injury and carcinogenesis. Methylation of rat-liver nucleic acids by dimethylnitrosamine in vivo.毒性肝损伤与致癌作用。二甲基亚硝胺在体内对大鼠肝脏核酸的甲基化作用。
Biochem J. 1962 Apr;83(1):114-24. doi: 10.1042/bj0830114.
7
STUDIES ON METHYLAZOXYMETHANOL, THE AGLYCONE OF CYCASIN. ISOLATION, BIOLOGICAL, AND CHEMICAL PROPERTIES.苏铁苷元甲基氧化甲醇的研究。分离、生物学及化学性质。
Arch Biochem Biophys. 1965 May;110:373-80. doi: 10.1016/0003-9861(65)90137-2.
8
CYCASIN: RADIOMIMETIC EFFECT.
Science. 1965 Jul 30;149(3683):541-2. doi: 10.1126/science.149.3683.541.
9
CARCINOGENIC EFFECTS OF CYCAD MEAL AND CYCASIN, METHYLAZOXYMETHANOL GLYCOSIDE, IN RATS AND EFFECTS OF CYCASIN IN GERMFREE RATS.苏铁粉和苏铁素（甲基氧化偶氮甲醇糖苷）对大鼠的致癌作用以及苏铁素对无菌大鼠的影响。
Fed Proc. 1964 Nov-Dec;23:1386-8.
10
EFFECT OF CYCAD AND CYCASIN FEEDING ON LIVER RNA, DNA, SUCCINIC OXIDASE, AND LIPIDS IN THE RAT.
Fed Proc. 1964 Nov-Dec;23:1374-5.