γ射线辐照对DNA和多核苷酸水合特性的影响。III. 冷冻溶液和液体溶液的核磁共振对比研究。
The effects of gamma-irradiation on the hydration characteristics of DNA and polynucleotides. III. A comparative NMR study of frozen and liquid solutions.
作者信息
Mathur-De Vré R, Bertinchamps A J
出版信息
Radiat Environ Biophys. 1977 Dec 12;14(4):311-5. doi: 10.1007/BF01325246.
PMID:594316
Abstract
The effects of gamma-irradiation and changes in the macromolecular structure on the water proton resonance spectra observed in frozen and liwuid solutions have been compared for the DNA and polynucleotide solutions, using H2O or mixed H2O/D2O solvents. The results indicate that in order to obtain information concerning the role of hydration water in mediating the overall radiation damage, the NMR studies must be performed in the frozen state.
摘要
对于DNA和多核苷酸溶液，使用H₂O或H₂O/D₂O混合溶剂，比较了γ射线辐照以及大分子结构变化对在冷冻溶液和液体溶液中观察到的水质子共振谱的影响。结果表明，为了获得有关水合水在介导整体辐射损伤中作用的信息，必须在冷冻状态下进行核磁共振研究。
Zotero 插件