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血管内凝血在免疫疾病中的致病作用。

Pathogenic role of intravascular coagulation in immune diseases.

作者信息

Papilian M, Purice S, Niţă I, Tanaăseanu S

出版信息

Med Interne. 1977 Oct-Dec;15(4):341-7.

PMID:594617
Abstract

The tests for the detection of intravascular coagulation and of secondary fibrinolysis performed in 79 patients with systemic lupus erythematosus and 30 patients with other collagenoses were positive in over 63% of the cases. A highly significant correlation was found between the presence of fibrinolytic degradation products (FDP) and the incidence of nephropathy and renal insufficiency, as well as between the presence of fibrin monomers (Godal's ethanol-gelification test) and the evolutive signs of the primary disease (fever, accelerated ESR).

摘要

对79例系统性红斑狼疮患者和30例其他胶原病患者进行的血管内凝血及继发性纤溶检测,结果超过63%的病例呈阳性。发现纤维蛋白溶解降解产物(FDP)的存在与肾病及肾功能不全的发生率之间存在高度显著相关性,同时纤维蛋白单体的存在(戈达尔乙醇凝胶化试验)与原发性疾病的进展迹象(发热、血沉加快)之间也存在高度显著相关性。

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1
Pathogenic role of intravascular coagulation in immune diseases.血管内凝血在免疫疾病中的致病作用。
Med Interne. 1977 Oct-Dec;15(4):341-7.
2
[Comparative study of various rapid methods of determining fibrinogen transformation products in the diagnosis of intravascular coagulation and fibrinolysis].[多种快速测定纤维蛋白原转化产物方法在血管内凝血与纤维蛋白溶解诊断中的比较研究]
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[Studies on plasma F. XIII subunit a level and the detection of soluble fibrin monomer in collagen diseases].[胶原病患者血浆F. XIII亚基a水平及可溶性纤维蛋白单体检测的研究]
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