X射线辐射和烷化剂作为恶性淋巴细胞增生性疾病自身免疫并发症可能的“触发”机制。
X-radiation and alkylating agents as possible "trigger" mechanisms in the autoimmune complications of malignant lymphophroliferative disease.
作者信息
Lewis F B, Schwartz R S, Dameshek W
出版信息
Clin Exp Immunol. 1966 Jan;1(1):3-11.
Abstract
One hundred patients with lymphoproliferative disease were reviewed. Seven of these patients were found to develop an autoimmune complication following the use of radiation or radiomimetic drug. The literature suggesting that radiation can enhance as well as suppress the autoimmune response is summarized, and the possibility that therapy can trigger autoimmunity in these patients is emphasized.
摘要
对100例淋巴增生性疾病患者进行了回顾性研究。其中7例患者在使用放疗或类放射药物后出现了自身免疫并发症。总结了提示放疗既能增强也能抑制自身免疫反应的文献，并强调了治疗可能引发这些患者自身免疫的可能性。
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