Atakhanova B A, Kadyrova K A, Saatov T S, Turakulov Ia Kh
Vopr Med Khim. 1977 Sep-Oct;23(5):606-8.
Analysis of proteins, synthesized in cell-free system using nodal euthyroid goiter, was carried out by polyacrylamide gel disc electrophoresis. Four protein farctions, incorporating labelled amino acids, were found: "complete" thyroglobulin, two its subunits and thyroalmbumin. This correlates with the concept that malignant cell synthesizes intensively proteins untypical for a normal tissue.
利用结节性甲状腺肿在无细胞系统中合成的蛋白质,通过聚丙烯酰胺凝胶圆盘电泳进行分析。发现了四个掺入标记氨基酸的蛋白质组分:“完整”甲状腺球蛋白、它的两个亚基和甲状腺白蛋白。这与恶性细胞大量合成正常组织中不典型蛋白质的概念相关。