Ivanitskaia V I, Nagulin Iu A, Tskhovrebov E A
Vopr Onkol. 1977;23(11):29-34.
The authors report the indications to and the results of clinical application of interstitial injections of iodine-131 in unresectable tumors, recurrences and regional metastases of thyroid cancer. Interstitial injection of iodine-131 in 35 inoperable patients (66 injections of iodine-131) made it possible to reduce considerably the size of tumor by 1 g of the tumor, on the average, were of the order of 5140 rad, radiation exposure of blood and kidneys--0.03 rad/litre and 139 rad, accordingly. Neither complications nor grave local and general reactions were noted.
作者报告了131碘间质注射在不可切除的甲状腺癌肿瘤、复发灶及区域转移灶中的临床应用指征及结果。对35例无法手术的患者进行了131碘间质注射(共注射66次),平均每1克肿瘤组织接受约5140拉德的照射后,肿瘤体积显著缩小,血液和肾脏的辐射暴露量分别为0.03拉德/升和139拉德。未观察到并发症以及严重的局部和全身反应。