Neĭman I M, Andrianova M M
Vopr Onkol. 1977;23(11):75-9.
Injection of 2 mg of methylcholanthrene renders a sensitizing effect on separate tissues and enhances the development of skin papillomas and cancer in skin application of methylcholanthrene. To the time of papillomas appearance sensitized animals showed immunosuppression being more significant than in nonsensitized mice. Animals with cancerous tumors, both sensitized and non-sensitized, showed paralysis of immunological mechanisms of the organism protection.
注射2毫克甲基胆蒽会对不同组织产生致敏作用，并在皮肤涂抹甲基胆蒽时增强皮肤乳头状瘤和癌症的发展。在乳头状瘤出现时，致敏动物表现出免疫抑制，比未致敏小鼠更为显著。患有癌性肿瘤的动物，无论是致敏的还是未致敏的，都表现出机体保护免疫机制的麻痹。
