Langer T, Berndt H
Z Gesamte Inn Med. 1977 Oct 1;32(19):Suppl: 290-3.
The matched pair analysis is a well-known, but rarely used method. This method is recommended for the following problems: preparation of a controlled clinical experiment based upon the results of a retrospective analysis of results of therapy; analysis of results from a controlled clinical experiment in sub-groups; influence of non-therapeutic factors on the prognosis; epidemiological problems and study of the course of diseases. A matched pair analysis of about 300 female patients with breast carcinoma failed to show significant differences between (a) radical mastectomy alone, (b) radical mastectomy followed by chemotherapy with cyclophosphamide, and (c) preoperative irradiation followed by radical mastectomy.
配对分析是一种广为人知但很少使用的方法。该方法适用于以下问题：根据治疗结果的回顾性分析准备对照临床试验；亚组中对照临床试验结果的分析；非治疗因素对预后的影响；流行病学问题以及疾病病程的研究。对约300名乳腺癌女性患者进行的配对分析未能显示出（a）单纯根治性乳房切除术、（b）根治性乳房切除术后用环磷酰胺化疗以及（c）术前放疗后行根治性乳房切除术之间存在显著差异。
