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[慢性缺血性心脏病患者血浆中乳酸脱氢酶(LDH)和谷草转氨酶(GOT)同工酶的术前、术中和术后表现]

[Pre-, intra- and postoperative behavior of LDH and GOT isoenzymes in the plasma of patients with chronic ischemic heart disease].

作者信息

Blätterlein I, Lehmann I, Wagenknecht C

出版信息

Z Gesamte Inn Med. 1977 Oct 15;32(20):suppl: 307-9.

PMID:595727
Abstract

The isoenzymes of LDH (types H and M) and the isoenzymes of GOT (cytoplasma, mitochondria) were examined in 14 male patients with chronic ischaemic heart disease before, during and after operation. The present study compares them with clinical parameters. Considering the combination of the two isoenzyme ratios, it can be generalized that chronic ischaemia of the heart is characterized both by a decrease of the ratio H : M of the LDH and an increase of the ratio M : C of the LDH and an increase of the ratio M : C of the GOT. Confirming the function of the open by-pass by recoronarography, the isoenzyme values are normal both with regard to their ratio and to their absolute values.

摘要

对14例慢性缺血性心脏病男性患者在手术前、手术期间及手术后检测了乳酸脱氢酶同工酶(H型和M型)以及谷草转氨酶同工酶(细胞质型、线粒体型)。本研究将这些同工酶与临床参数进行了比较。综合考虑两种同工酶比率,一般而言,慢性心肌缺血的特征在于乳酸脱氢酶H:M比率降低、乳酸脱氢酶M:C比率升高以及谷草转氨酶M:C比率升高。经冠状动脉造影证实搭桥通畅,同工酶值在比率及绝对值方面均正常。

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