Vinogradova O S, Brazhnik E S
Zh Vyssh Nerv Deiat Im I P Pavlova. 1977 Nov-Dec;27(6):1166-72.
Investigation of neuronal activity on non-anaesthetized rabbits in non-stress chronic conditions revealed in the hippocampus a small proportion of neurones (10-12 percent) with a weak rhythmic (theta) modulation of their activity. In the medial and lateral septal nuclei this activity was more organized and was present in about one third of neuronal population. Disruption of septo-hippocampal connections completely abolished theta-rhythm in EEG and in neuronal activity of the hippocampus. Transection of the perforant path was followed by appearance of pronounced theta-bursts in a large group of neurones (38 percent in CA1 and 43 percent in CA3). Electrical stimulation of the hippocampus suppressed theta-bursts and decreased their frequency in the lateral spetal nucleus. Disruption of hippocampo-septal connections was followed by an increase of the population of septal neurones with theta-bursts (48 percent), which became more prounced. Some theoretical implications from these data concerning the nature of hippocampal theta-activity are discussed.
在非应激慢性条件下对未麻醉兔子的神经元活动进行研究发现，海马体中有一小部分神经元（10%-12%）其活动具有微弱的节律性（θ）调制。在内侧和外侧隔核中，这种活动更有组织性，约三分之一的神经元群体存在这种活动。切断隔-海马连接完全消除了脑电图中的θ节律以及海马体的神经元活动。切断穿通通路后，一大群神经元（CA1区为38%，CA3区为43%）出现明显的θ爆发。对海马体进行电刺激可抑制θ爆发并降低其在外侧隔核中的频率。切断海马-隔连接后，出现θ爆发的隔神经元群体增加（48%），且变得更加明显。讨论了这些数据对海马体θ活动性质的一些理论启示。
