Ebeling K, Ruckhäberle K E, Bilek K
Zentralbl Gynakol. 1977;99(20):1249-59.
Organ cultures are a suitable in vitro test--object for pretherapeutical testing of cytostatic resistance on carcinomas of the cervix uteri. The decrease of activity of lactic dehydrogenase and isocitric acid dehydrogenase, determined histochemically, can be used to monitor cytostatic effects at the cultivated tumour. In preparing chemotherapy schedules for advanced cervical carcinomas, cytostatic agents provedly ineffective in vitro should be avoided.
器官培养是子宫颈癌细胞抑制抗性治疗前测试的合适体外试验对象。通过组织化学方法测定的乳酸脱氢酶和异柠檬酸脱氢酶活性的降低，可用于监测培养肿瘤中的细胞抑制作用。在制定晚期子宫颈癌的化疗方案时，应避免使用在体外已证明无效的细胞抑制剂。
