Ruckhäberle K E, Franke J, Viehweg B, Gerl D
Zentralbl Gynakol. 1977;99(21):1313-22.
A total of 45 placentae of different gestatory age were used to study, after clinically and anamnestically normal pregnancy and by a morphometric method, the quantitative behavior of individual parts of the placental barrier in the course of gestation. For this, hematoxylin-stained preparations and enzyme-incubated semi-thin sections were used. The increase in the percentage of fetal vascular surface with a simultaneous decrease in the relative percentage of villous surface (when determining the ratio of villous surface surrounded by maternal blood to the fetal vascular surface) up to the 28th week of gestation must be considered an expression of an increase in the capability of function. The simultaneous distinct decrease in the average number of Langhans cells and the reduction of their less differentiated forms in favor of those showing a higher degree of differentiation allow to make the conclusion that around the 28th week of gestation conditions in individual villi are, in general, similar to those prevailing in term placentae between the 37th and 41st weeks of gestation. The results obtained from the basis of quantitative studies of the placentae of premature infants and babies born at term after different gestatory risks.
选取45个不同孕周的胎盘用于研究，这些胎盘来自临床及既往史均正常的妊娠。通过形态计量学方法，研究胎盘屏障各部分在妊娠过程中的定量变化。为此，使用苏木精染色制剂和酶孵育半薄切片。直至妊娠第28周，胎儿血管表面积百分比增加，同时绒毛表面积相对百分比下降（测定母体血液包围的绒毛表面积与胎儿血管表面积之比时），这一现象必须被视为功能能力增强的表现。朗汉斯细胞平均数量同时显著减少，且其分化程度较低的形式减少，有利于分化程度较高的形式，由此可以得出结论，在妊娠第28周左右，单个绒毛的情况总体上与妊娠37至41周足月胎盘的情况相似。这些结果是基于对不同妊娠风险后早产婴儿和足月出生婴儿的胎盘进行定量研究得出的。
