Cluster headache associated with primary hyperlipidemia.

Two brothers suffering from cluster headache of the chronic variant as well as hyperlipidemia are described. The mother very likely suffered from the same combination. Eleven consecutive cases of cluster headache were studied for lipid abnormalities. Among five patients of the intermittent type, one suffereed from xantelasmata but had normal blood lipids. Among six patients of the chronic variant two had essential hyperlipidemia type IV. An etiological relationship between some cases of cluster headache and hyperlipidemia is therefore suggested.