Ekström J, Templeton D
Acta Physiol Scand. 1977 Nov;101(3):329-35. doi: 10.1111/j.1748-1716.1977.tb06014.x.
The sensitivity to methacholine of the parotid glands in rats maintained on a liquid diet (aiming at sensitization) for a period of 2 weeks or 3-4 weeks was compared with that of the parotid glands in rats on a pelleted bulk diet (aiming at desensitization). In the rats on the liquid diet, it was found that the dose needed to evoke a just perceptible secretion of saliva was smaller, that the secretion started earlier and continued over a longer time period, and further that the amount of saliva secreted expressed per gland weight in response to submaximal doses of the sialogogue drug was bigger when compared with the rats on the pelleted bulk diet. These findings are interpreted as signs of a higher degree of sensitivity of the glands in the rats on the liquid diet than of those in the rats on the pelleted bulk diet.
将持续2周或3 - 4周食用流质饮食（旨在致敏）的大鼠腮腺对乙酰甲胆碱的敏感性与食用颗粒状大量饮食（旨在脱敏）的大鼠腮腺进行比较。在食用流质饮食的大鼠中，发现引起刚可察觉唾液分泌所需的剂量较小，分泌开始得更早且持续时间更长，并且与食用颗粒状大量饮食的大鼠相比，在亚最大剂量的催涎药物作用下，按每腺体重量计算分泌的唾液量更大。这些发现被解释为食用流质饮食的大鼠腺体比食用颗粒状大量饮食的大鼠腺体具有更高敏感性的迹象。
