地高辛及其代谢产物的蛋白质结合比较研究。
Comparative studies of the protein binding of digoxin and its metabolites.
作者信息
Hinderling P H
出版信息
Agents Actions. 1977 Sep;7(3):379-82. doi: 10.1007/BF01969571.
PMID:596321
Abstract
The protein binding of Digoxin (D), Dihydrodigoxin (DH), Digoxigenin Bisdigitoxoside (DB) and Digoxigenin Monodigitoxoside (DM) was concentration independent and unaltered by the presence of high concentrations of the analogous compounds. The respective percentage of protein binding for D, DH, DB and DM were 22%, 22%, 23% and 27%.
摘要
地高辛（D）、二氢地高辛（DH）、洋地黄毒苷双洋地黄毒糖甙（DB）和洋地黄毒苷单洋地黄毒糖甙（DM）的蛋白结合率与浓度无关，且不受高浓度类似化合物存在的影响。D、DH、DB和DM各自的蛋白结合率分别为22%、22%、23%和27%。
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