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Hydrolysis of neutral substrates by acetylcholinesterase.

作者信息

Krupka R M

出版信息

Biochemistry. 1966 Jun;5(6):1983-8. doi: 10.1021/bi00870a028.

DOI:10.1021/bi00870a028
PMID:5963442
Abstract
摘要

相似文献

1
Hydrolysis of neutral substrates by acetylcholinesterase.乙酰胆碱酯酶对中性底物的水解作用。
Biochemistry. 1966 Jun;5(6):1983-8. doi: 10.1021/bi00870a028.
2
[The effect of quaternary ammonium compounds on the hydrolysis of various substrates that is catalyzed by specific and nonspecific cholinesterases].[季铵化合物对由特异性和非特异性胆碱酯酶催化的各种底物水解的影响]
Ukr Biokhim Zh. 1973;45(1):70-5.
3
ACETYLCHOLINESTERASE: TRIMETHYLAMMONIUM-ION INHIBITION OF DEACETYLATION.乙酰胆碱酯酶：三甲铵离子对脱乙酰作用的抑制
Biochemistry. 1964 Nov;3:1749-54. doi: 10.1021/bi00899a029.
4
ARE IDENTICAL CATALYTIC GROUPS INVOLVED IN THE ACETYLATION AND DEACETYLATION STEPS OF ACETYLCHOLINESTERASE REACTIONS?参与乙酰胆碱酯酶反应的乙酰化和去乙酰化步骤的催化基团是否相同？
Biochem Biophys Res Commun. 1965 May 3;19:531-7. doi: 10.1016/0006-291x(65)90158-0.
5
[Cholinesterase hydrolysis of acetylcholine derivatives with different structures of the ammonium grouping].[具有不同铵基结构的乙酰胆碱衍生物的胆碱酯酶水解作用]
Biokhimiia. 1975 Jan-Feb;40(1):95-102.
6
Kinetic studies on the mechanism of insect acetylcholinesterase.
Biochemistry. 1970 Nov 24;9(24):4665-72. doi: 10.1021/bi00826a008.
7
Conformational aspects of systems related to acetylcholine. 3. Base-catalyzed and acetylcholinesterase-catalyzed hydrolysis of the isomeric dl-3-trimethylammonium-2-acetoxy-trans-decalin halides and the isomeric dl-1-methyl-3-acetoxy-trans-decahydroquinoline methiodides.与乙酰胆碱相关体系的构象方面。3. 异构的dl - 3 - 三甲基铵 - 2 - 乙酰氧基 - 反式十氢化萘卤化物和异构的dl - 1 - 甲基 - 3 - 乙酰氧基 - 反式十氢喹啉甲碘化物的碱催化及乙酰胆碱酯酶催化水解。
J Med Chem. 1972 Mar;15(3):241-3. doi: 10.1021/jm00273a009.
8
The catalytic versatility of erythrocyte carbonic anhydrase. 3. Kinetic studies of the enzyme-catalyzed hydrolysis of p-nitrophenyl acetate.红细胞碳酸酐酶的催化多样性。3. 对硝基苯乙酸酶催化水解的动力学研究。
Biochemistry. 1967 Mar;6(3):668-78. doi: 10.1021/bi00855a005.
9
[On the inhibition of the acetylcholine hydrolysis rate by bovine erythrocyte acetylcholinesterase in the presence of high concentration of substrate].
Biokhimiia. 1965 Nov-Dec;30(6):1154-9.
10
The acceleration of acetylcholinesterase activity at low ionic strength by organic and inorganic cations.
Mol Pharmacol. 1968 Mar;4(2):181-6.

引用本文的文献

1
Acetylcholinesterase: evidence that sodium ion binding at the anionic site causes inhibition of the second-order hydrolysis of acetylcholine and a decrease of its pKa as well as of deacetylation.乙酰胆碱酯酶：有证据表明，钠离子结合于阴离子位点会抑制乙酰胆碱的二级水解，并降低其pKa以及脱乙酰作用。
Biochem J. 1981 Jul 1;197(1):163-70. doi: 10.1042/bj1970163.
2
Human erythrocyte acetylcholinesterase in relation to cell age.与细胞年龄相关的人红细胞乙酰胆碱酯酶
Biochem J. 1981 Apr 1;195(1):221-8. doi: 10.1042/bj1950221.
3
Effect of pH on inhibition and spontaneous reactivation of acetylcholinesterase treated with esters of phosphorus acids and of carbamic acids.
pH对用磷酸酯和氨基甲酸酯处理的乙酰胆碱酯酶抑制及自发复活的影响
Biochem J. 1967 Oct;105(1):171-9. doi: 10.1042/bj1050171.
4
The inhibition of acetylcholinesterase by oxime carbamates.肟类氨基甲酸酯对乙酰胆碱酯酶的抑制作用。
Biochem J. 1969 Aug;114(1):14P-15P. doi: 10.1042/bj1140014pb.
5
Anionic subsites of the acetylcholinesterase from Torpedo californica: affinity labelling with the cationic reagent N,N-dimethyl-2-phenyl-aziridinium.加州电鳐乙酰胆碱酯酶的阴离子亚位点：用阳离子试剂N,N-二甲基-2-苯基氮丙啶进行亲和标记
EMBO J. 1990 Dec;9(12):3885-8. doi: 10.1002/j.1460-2075.1990.tb07607.x.
6
Mutagenesis of essential functional residues in acetylcholinesterase.
Proc Natl Acad Sci U S A. 1990 Oct;87(19):7546-50. doi: 10.1073/pnas.87.19.7546.
7
Anionic subsites of the catalytic center of acetylcholinesterase from Torpedo and from cobra venom.电鳐和眼镜蛇毒中乙酰胆碱酯酶催化中心的阴离子亚位点。
Proc Natl Acad Sci U S A. 1991 Jul 15;88(14):6117-21. doi: 10.1073/pnas.88.14.6117.
8
Substrate inhibition of acetylcholinesterase: residues affecting signal transduction from the surface to the catalytic center.乙酰胆碱酯酶的底物抑制作用：影响从表面到催化中心信号转导的残基
EMBO J. 1992 Oct;11(10):3561-8. doi: 10.1002/j.1460-2075.1992.tb05439.x.