Vas R, Diamond G A, Wyatt H L, da Luz P L, Swan H J, Forrester J S
Am J Physiol. 1977 Dec;233(6):H700-6. doi: 10.1152/ajpheart.1977.233.6.H700.
The validity of a new noninvasive device, the cardiokymograph, was assessed as to its ability to detect regional myocardial wall motion by direct comparison of the analog tracing with that of an epicardial length gauge in 11 open-chest dogs. The correlation of the two methods was excellent both during control conditions and following changes induced by acute coronary occlusion. The average difference between the methods in timing of various cardiac events was only 6.2 +/- 1.9 ms at rest and 6.8 +/- 1.5 ms following ischemia (P = NS). Relative amplitude ratio correlations, determined for the four portions of the cardiac cyele (isovolumic systole, ejection, isovolumic relaxation, and diastole), were also excellent. The average correlation of the kymograph to the length gauge was r = 0.896 +/- 0.018 at rest (K = 0.977 LG + 0.033) and r = 0.932 +/- 0.013 following occlusion (K = 1.071 LG + 0.101). Thus, the cardiokymograph is a sensitive and accurate noninvasive method for detection of regional ischemic dysfunction and produces an analog tracing essentially identical to that of the epicardial length gauge.
通过在11只开胸犬中直接比较模拟描记图与心外膜长度测量仪的结果，评估了一种新型非侵入性设备——心动描记仪检测局部心肌壁运动的能力。在对照条件下以及急性冠状动脉闭塞引起变化后，两种方法的相关性都非常好。在静息状态下，两种方法在各种心脏事件发生时间上的平均差异仅为6.2±1.9毫秒，缺血后为6.8±1.5毫秒（P=无显著性差异）。针对心动周期的四个部分（等容收缩期、射血期、等容舒张期和舒张期）确定的相对振幅比相关性也非常好。静息时心动描记图与长度测量仪的平均相关性为r=0.896±0.018（K=0.977LG+0.033），闭塞后为r=0.932±0.013（K=1.071LG+0.101）。因此，心动描记仪是一种检测局部缺血性功能障碍的灵敏且准确的非侵入性方法，其产生的模拟描记图与心外膜长度测量仪的基本相同。
