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哥斯达黎加利蒙港的班氏丝虫病。

Bancroftian filariasis in Puerto Limón, Costa Rica.

作者信息

Weinstock H, Paniagua F, Garcés J L, Zúñiga A, Granados C, Hernández E

出版信息

Am J Trop Med Hyg. 1977 Nov;26(6 Pt 1):1148-52. doi: 10.4269/ajtmh.1977.26.1148.

DOI:10.4269/ajtmh.1977.26.1148
PMID:596512
Abstract

In four neighborhoods of Puerto Limón, a Caribbean coastal city in a tropical rainforest area of Costa Rica, examination of 1-ml samples of night blood from 1,142 randomly selected, and 1,196 associated, persons by the Knott and filter-chamber techniques revealed microfilariae of Wuchereria bancrofti in about 3% of the 2,338 samples. The frequency of infection was higher in males (3.9%) than in females (1.9%), higher in persons of black (4.1%) than of white (1.0%) race, and highest in persons aged 10-19 (4.0%) and over 50 years (4.8%), lowest in those under 10 years (1.1%). The median microfilaria density was 3.5, the highest 45, per 20 lambdas of blood. Microfilaremia was distinctly periodic. Dissection of 663 female Culex pipiens fatigans from 42 houses of infected persons revealed filarial larvae in 25; only 1 larva was third (infective) stage. Of 64 infected persons, 11 had clinical findings suggestive of filariasis. Elephantiasis was seen in 21 others. Other forms of symptomatic filariasis without microfilaremia, though presumed to be present, were not assessed specifically.

摘要

在哥斯达黎加热带雨林地区的加勒比沿海城市利蒙港的四个社区,采用诺特氏法和滤膜法对随机抽取的1142名及与之相关的1196人的1毫升夜间血液样本进行检测,发现在2338份样本中约3%存在班氏吴策线虫微丝蚴。男性感染率(3.9%)高于女性(1.9%),黑人(4.1%)高于白人(1.0%),10 - 19岁人群(4.0%)和50岁以上人群(4.8%)感染率最高,10岁以下人群(1.1%)最低。每20微升血液中微丝蚴密度中位数为3.5,最高为45。微丝蚴血症具有明显的周期性。对来自42户感染者家中的663只致倦库蚊雌蚊进行解剖,发现25只体内有丝虫幼虫;只有1只为三期(感染期)幼虫。64名感染者中,11人有提示丝虫病的临床表现。另外21人有象皮肿。虽然推测存在其他无微丝蚴血症的有症状丝虫病形式,但未进行具体评估。

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