从橡胶树胶乳中分离出δ-生育三烯酚及其性质
The isolation and properties of delta-tocotrienol from Hevea latex.
作者信息
Whittle K J, Dunphy P J, Pennock J F
出版信息
Biochem J. 1966 Jul;100(1):138-45. doi: 10.1042/bj1000138.
Abstract
- delta-Tocotrienol (8-methyltocotrienol) was isolated from the latex of Hevea brasiliensis. This new member of the tocopherol family is a pale-yellow oil at room temperature. 2. The properties of delta-tocotrienol are very similar to those of delta-tocopherol and the small differences can be explained by the change in side chain. 3. The ultraviolet and infrared spectra of delta-tocotrienol were determined and a conversion factor for use with the Emmerie-Engel reaction was worked out. Details are given for the chromatography of delta-tocotrienol on thin layers (adsorption and partition) and reversed-phase paper, and the nitroso derivatives were formed. 4. An ethyl carbonate ester of delta-tocotrienol was prepared and compared with a similar ester of delta-tocopherol. 5. Hydroxymethylation of delta-tocotrienol followed by reduction gave beta-tocotrienol as a major product.
摘要
- δ-生育三烯酚（8-甲基生育三烯酚）是从巴西橡胶树的乳胶中分离出来的。生育酚家族的这个新成员在室温下是一种淡黄色油状物。2. δ-生育三烯酚的性质与δ-生育酚非常相似，其细微差异可由侧链的变化来解释。3. 测定了δ-生育三烯酚的紫外光谱和红外光谱，并得出了用于埃默里-恩格尔反应的换算因子。给出了δ-生育三烯酚在薄层（吸附和分配）和反相纸上的色谱分析细节，并形成了亚硝基衍生物。4. 制备了δ-生育三烯酚的碳酸乙酯，并与δ-生育酚的类似酯进行了比较。5. δ-生育三烯酚经羟甲基化后再还原，得到β-生育三烯酚作为主要产物。
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本文引用的文献
1
Skin sterols. II. Isolation of delta 7-cholesterol.皮肤甾醇。II. Δ7-胆固醇的分离
J Biol Chem. 1952 Apr;195(2):623-8.
2
Preparation of lipide extracts from brain tissue.脑组织脂质提取物的制备。
J Biol Chem. 1951 Aug;191(2):833-41.
3
Substance SC (ubichromenol): a naturally-occurring cyclic isomeride of ubiquinone-50.物质SC（泛色烯醇）：一种天然存在的辅酶Q-50的环状异构体。
Biochem J. 1960 Mar;74(3):541-9. doi: 10.1042/bj0740541.
4
VITAMIN E CONTENT OF VEGETABLE OILS AND FATS.植物油和脂肪中的维生素E含量。
J Nutr. 1963 Dec;81(4):335-42. doi: 10.1093/jn/81.4.335.
5
TOCOPHEROL CONTENTS OF VEGETABLES AND FRUITS.
Br J Nutr. 1963;17:575-81. doi: 10.1079/bjn19630060.
6
A method for separating lipid components of leaves.一种分离叶片脂质成分的方法。
Biochem J. 1962 Aug;84(2):444-8. doi: 10.1042/bj0840444.
7
Biological potencies of epsilon- and zeta-1-tocopherol and 5-methyltocol.ε-生育酚、ζ-1-生育酚和5-甲基生育三烯酚的生物活性
Br J Nutr. 1961;15:253-7. doi: 10.1079/bjn19610030.
8
Eta-Tocopherol (7-methyltocol) a new tocopherol in rice.
Nature. 1956 Jan 14;177(4498):86-7. doi: 10.1038/177086b0.
9
A reassessment of tocopherol in chemistry.化学中生育酚的重新评估。
Biochem Biophys Res Commun. 1964 Nov 30;17(5):542-8. doi: 10.1016/0006-291x(64)90062-2.
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