胸腺提取物对肌肉和血清中磷化合物以及血清钙的影响。
The effect of thymus extracts on phosphorus compounds in muscle and serum, and on serum calcium.
作者信息
Potop I, Boeru V, Mreană G
出版信息
Biochem J. 1966 Nov;101(2):454-9. doi: 10.1042/bj1010454.
Abstract
- Thymectomy in young rabbits decreased the ATP content and increased the inorganic phosphate content of skeletal muscle. The serum calcium content was decreased, whereas the inorganic phosphate content was increased. 2. The administration of a lipid fraction (TL) or protein fractions (CIF and TP) of thymus extracts to thymectomized rabbits in short-term experiments increased the ATP content of muscle and decreased the inorganic phosphate contents of muscle and serum. Serum calcium content was increased. 3. The action of the thymus extract TP was specific only on the phosphate compounds, since the increase in serum calcium concentration was also caused by the control extract from muscle. The action of the extract TL is not specific, being paralleled by the action of a control extract from muscle.
摘要
- 对幼兔进行胸腺切除会降低骨骼肌的三磷酸腺苷（ATP）含量，并增加无机磷酸盐含量。血清钙含量降低，而无机磷酸盐含量增加。2. 在短期实验中，给胸腺切除的兔子注射胸腺提取物的脂质部分（TL）或蛋白质部分（CIF和TP），可增加肌肉的ATP含量，并降低肌肉和血清中的无机磷酸盐含量。血清钙含量增加。3. 胸腺提取物TP的作用仅对磷酸盐化合物具有特异性，因为血清钙浓度的升高也可由肌肉的对照提取物引起。提取物TL的作用不具有特异性，肌肉对照提取物的作用与之相似。
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