Van Vleet J F, Ferrans V J
Am J Vet Res. 1977 Dec;38(12):2077-80.
Three 5-week-old pigs from an Indiana farm died of the cardiac form ("mulberry heart disease") of selenium-vitamin E deficiency. Grossly, the hearts had prominent hydropericardium and extensive serosal and myocardial hemorrhage. Histopathologic study demonstrated marked myocardial edema, congestion, and hemorrhage, with numerous capillary hyaline microthrombi that stained red with the periodic-acid Schiff rocedure. Ultrastructural study revealed that these thrombi were composed of elongated, dense masses of intertwined fibrin strands with occasional entrapped erythrocytes.
来自印第安纳州一个农场的3头5周龄仔猪死于硒-维生素E缺乏症的心脏型（“桑葚心疾病”）。大体上，心脏有明显的心包积水以及广泛的浆膜和心肌出血。组织病理学研究显示明显的心肌水肿、充血和出血，有许多用高碘酸希夫染色法染成红色的毛细血管透明微血栓。超微结构研究显示这些血栓由交织的纤维蛋白丝构成的细长致密团块组成，偶尔有被困的红细胞。
