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[鸡的胸腺切除术与淋巴细胞介导的细胞毒性作用(作者译)]

[Thymectomy and lymphocyte mediated cytotoxicity in the chicken (author's transl)].

作者信息

Dambrine G, Coudert F, Cauchy L

出版信息

Ann Immunol (Paris). 1977 Nov-Dec;128(6):1091-5.

PMID:596836
Abstract

Spleen and blood lymphocytes from non-thymectomized chicken immunized with sheep red blood cells are cytotoxic in vitro against 51Cr-labelled sheep red blood cells with specific lysis values in the order of 40%. Complete Freund's adjuvant is necessary to obtain a measurable degree of specific lysis. Spleen and blood from immunized thymectomized chicken yield little or no cytotoxic lymphocytes, with specific lysis values inferior to 15%, whatever the number of added lymphocytes.

摘要

用绵羊红细胞免疫的未切除胸腺的鸡的脾脏和血液淋巴细胞在体外对51Cr标记的绵羊红细胞具有细胞毒性,特异性裂解值约为40%。要获得可测量程度的特异性裂解,完全弗氏佐剂是必需的。无论添加淋巴细胞的数量如何,来自免疫的切除胸腺的鸡的脾脏和血液产生的细胞毒性淋巴细胞很少或没有,特异性裂解值低于15%。

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