注入麻醉犬脑室的单胺类物质对体温的影响。
Effects on temperature of monoamines injected into the cerebral ventricles of anaesthetized dogs.
作者信息
Feldberg W, Hellon R F, Myers R D
出版信息
J Physiol. 1966 Oct;186(2):416-23. doi: 10.1113/jphysiol.1966.sp008043.
Abstract
- In dogs anaesthetized with pentobarbitone sodium an injection of adrenaline or noradrenaline into the cerebral ventricles through a cannula implanted into the left lateral ventricle caused a fall in rectal temperature as a result of cessation of shivering, loss of muscle tone, and skin vasodilatation. 5-Hydroxytryptamine (5-HT) similarly applied caused shivering and a rise in rectal temperature.2. The hypothalamus of the dog thus appears to react to the three monoamines in the same way as in the cat, and not as in the rabbit and sheep.
摘要
- 在用戊巴比妥钠麻醉的狗身上，通过植入左侧脑室的套管向脑室注射肾上腺素或去甲肾上腺素，会导致直肠温度下降，这是由于寒战停止、肌肉张力丧失和皮肤血管扩张所致。同样应用5-羟色胺（5-HT）会引起寒战和直肠温度升高。2. 因此，狗的下丘脑对这三种单胺的反应似乎与猫相同，而与兔子和绵羊不同。
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本文引用的文献
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J Physiol. 1965 Mar;177(2):239-45. doi: 10.1113/jphysiol.1965.sp007589.
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J Physiol. 1964 Dec;175(3):464-78. doi: 10.1113/jphysiol.1964.sp007527.
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