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注入麻醉犬脑室的单胺类物质对体温的影响。

Effects on temperature of monoamines injected into the cerebral ventricles of anaesthetized dogs.

作者信息

Feldberg W, Hellon R F, Myers R D

出版信息

J Physiol. 1966 Oct;186(2):416-23. doi: 10.1113/jphysiol.1966.sp008043.

DOI:10.1113/jphysiol.1966.sp008043
PMID:5972116
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1395844/
Abstract
  1. In dogs anaesthetized with pentobarbitone sodium an injection of adrenaline or noradrenaline into the cerebral ventricles through a cannula implanted into the left lateral ventricle caused a fall in rectal temperature as a result of cessation of shivering, loss of muscle tone, and skin vasodilatation. 5-Hydroxytryptamine (5-HT) similarly applied caused shivering and a rise in rectal temperature.2. The hypothalamus of the dog thus appears to react to the three monoamines in the same way as in the cat, and not as in the rabbit and sheep.
摘要
  1. 在用戊巴比妥钠麻醉的狗身上，通过植入左侧脑室的套管向脑室注射肾上腺素或去甲肾上腺素，会导致直肠温度下降，这是由于寒战停止、肌肉张力丧失和皮肤血管扩张所致。同样应用5-羟色胺（5-HT）会引起寒战和直肠温度升高。2. 因此，狗的下丘脑对这三种单胺的反应似乎与猫相同，而与兔子和绵羊不同。

相似文献

1
Effects on temperature of monoamines injected into the cerebral ventricles of anaesthetized dogs.注入麻醉犬脑室的单胺类物质对体温的影响。
J Physiol. 1966 Oct;186(2):416-23. doi: 10.1113/jphysiol.1966.sp008043.
2
The mechanism of body temperature changes induced by intraventricular injections of adrenaline, noradrenaline and 5-hydroxytryptamine in the ox (Bos taurus).脑室注射肾上腺素、去甲肾上腺素和5-羟色胺对牛（Bos taurus）体温变化的影响机制。
J Physiol. 1967 Apr;189(2):329-36. doi: 10.1113/jphysiol.1967.sp008171.
3
Temperature effects produced in dogs and monkeys by injections of monoamines and related substances into the third ventricle.通过向第三脑室注射单胺及相关物质在狗和猴子身上产生的温度效应。
J Physiol. 1967 Aug;191(3):501-15. doi: 10.1113/jphysiol.1967.sp008264.
4
Body temperature responses in cats and rabbits to the monoamine oxidase inhibitor tranylcypromine.猫和兔子对单胺氧化酶抑制剂反苯环丙胺的体温反应。
J Physiol. 1967 May;190(1):203-20. doi: 10.1113/jphysiol.1967.sp008202.
5
Effect of 5-hydroxytryptophan acting from the cerebral ventricles on 5-hydroxytryptamine output and body temperature.从脑室注入5-羟色氨酸对5-羟色胺分泌及体温的影响。
J Physiol. 1966 Oct;186(2):401-15. doi: 10.1113/jphysiol.1966.sp008042.
6
The effect of intraventricular injections of noradrenaline, 5-hydroxytryptamine, acetylcholine and tranylcypromine on the ox (Bos taurus) at different environmental temperatures.脑室内注射去甲肾上腺素、5-羟色胺、乙酰胆碱和反苯环丙胺对不同环境温度下牛（Bos taurus）的影响。
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[New experimental results in the hypothalamus].[下丘脑的新实验结果]
Acta Neuroveg (Wien). 1967;30(1):169-89. doi: 10.1007/BF01239892.
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Effect on temperature of 5-hydroxytryptamine injected into the cerebral ventricles of cats.向猫脑室注射5-羟色胺对体温的影响。
J Physiol. 1968 Mar;195(1):245-51. doi: 10.1113/jphysiol.1968.sp008456.
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Changes in body temperature produced by cholinomimetic substances injected into the cerebral ventricles of unanaesthetized cats.向未麻醉猫的脑室注射拟胆碱物质所产生的体温变化。
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10
Monoamine oxidase inhibition: effect on 5-hydroxytryptamine output from perfused third ventricle and body temperature.单胺氧化酶抑制作用：对灌注第三脑室中5-羟色胺输出及体温的影响。
J Physiol. 1967 Jan;188(1):131-40. doi: 10.1113/jphysiol.1967.sp008129.

引用本文的文献

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J Physiol. 1967 Nov;193(2):359-73. doi: 10.1113/jphysiol.1967.sp008362.
2
Temperature changes produced by the injection of catecholamines and 5-hydroxytryptamine into the cerebral ventricles of the conscious mouse.向清醒小鼠脑室注射儿茶酚胺和5-羟色胺所产生的体温变化。
J Physiol. 1967 Oct;192(3):805-13. doi: 10.1113/jphysiol.1967.sp008332.
3
Two components of facilitation at the neuromuscular junction of the frog.青蛙神经肌肉接头处易化作用的两个组成部分。
J Physiol. 1967 Jul;191(1):19P-20P.
4
The mechanism of body temperature changes induced by intraventricular injections of adrenaline, noradrenaline and 5-hydroxytryptamine in the ox (Bos taurus).脑室注射肾上腺素、去甲肾上腺素和5-羟色胺对牛（Bos taurus）体温变化的影响机制。
J Physiol. 1967 Apr;189(2):329-36. doi: 10.1113/jphysiol.1967.sp008171.
5
Rat brain amines, blood histamine and glucose levels in relationship to circadian changes in sleep induced by pentobarbitone sodium.大鼠脑胺、血液组胺和葡萄糖水平与戊巴比妥钠诱导睡眠的昼夜节律变化的关系。
J Physiol. 1969 May;202(1):133-46. doi: 10.1113/jphysiol.1969.sp008799.
6
The effect of intraventricular injections of noradrenaline, 5-hydroxytryptamine, acetylcholine and tranylcypromine on the ox (Bos taurus) at different environmental temperatures.脑室内注射去甲肾上腺素、5-羟色胺、乙酰胆碱和反苯环丙胺对不同环境温度下牛（Bos taurus）的影响。
J Physiol. 1968 Feb;194(3):809-16. doi: 10.1113/jphysiol.1968.sp008436.
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Influence of ambient temperature on the thermoregulatory responses to 5-hydroxytryptamine, noradrenaline and acetylcholine injected into the lateral cerebral ventricles of sheep, goats and rabbits.环境温度对绵羊、山羊和家兔侧脑室注射5-羟色胺、去甲肾上腺素和乙酰胆碱后体温调节反应的影响。
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J Physiol. 1968 Sep;198(2):345-53. doi: 10.1113/jphysiol.1968.sp008610.
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Exp Brain Res. 1969;8(4):295-310. doi: 10.1007/BF00234377.
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Control of body temperature in the unanaesthetized monkey by cholinergic and aminergic systems in the hypothalamus.下丘脑胆碱能和胺能系统对未麻醉猴体温的调节
J Physiol. 1969 Jun;202(2):483-500. doi: 10.1113/jphysiol.1969.sp008822.

本文引用的文献

1
CHANGES IN TEMPERATURE PRODUCED BY MICRO-INJECTIONS OF AMINES INTO THE ANTERIOR HYPOTHALAMUS OF CATS.向猫的下丘脑前部微量注射胺类物质所产生的温度变化。
J Physiol. 1965 Mar;177(2):239-45. doi: 10.1113/jphysiol.1965.sp007589.
2
TEMPERATURE CHANGES PRODUCED BY AMINES INJECTED INTO THE CEREBRAL VENTRICLES DURING ANAESTHESIA.麻醉期间注入脑室的胺类物质所产生的温度变化
J Physiol. 1964 Dec;175(3):464-78. doi: 10.1113/jphysiol.1964.sp007527.
3
EFFECTS ON TEMPERATURE OF AMINES INJECTED INTO THE CEREBRAL VENTRICLES. A NEW CONCEPT OF TEMPERATURE REGULATION.注入脑室的胺类对体温的影响。体温调节的新概念。
J Physiol. 1964 Sep;173(2):226-31. doi: 10.1113/jphysiol.1964.sp007454.
4
A NEW CONCEPT OF TEMPERATURE REGULATION BY AMINES IN THE HYPOTHALAMUS.下丘脑胺类物质调节体温的新概念。
Nature. 1963 Dec 28;200:1325. doi: 10.1038/2001325a0.
5
[Narcotic effects of intracisternal adrenalin injection].[脑池内注射肾上腺素的麻醉作用]
Anaesthesist. 1957 Apr;6(2):131-5.
6
Behaviour of cats after intraventricular injections of eserine and DFP.猫脑室内注射毒扁豆碱和二异丙基氟磷酸酯后的行为表现。
J Physiol. 1954 Sep 28;125(3):488-500. doi: 10.1113/jphysiol.1954.sp005175.
7
Injections of drugs into the lateral ventricle of the cat.将药物注射到猫的侧脑室。
J Physiol. 1954 Jan;123(1):148-67. doi: 10.1113/jphysiol.1954.sp005040.
8
Effects of intraventricular and intrahypothalamic injection of noradrenaline and 5-HT on body temperature in conscious rabbits.脑室内和下丘脑内注射去甲肾上腺素和5-羟色胺对清醒家兔体温的影响。
J Physiol. 1965 Dec;181(4):852-64. doi: 10.1113/jphysiol.1965.sp007801.