氨基酸对L-木糖和D-木糖体外肠道转运的影响。
The effect of amino acids on the intestinal transport of L- and D-xylose in vitro.
作者信息
Duthie H L, Hindmarsh J T
出版信息
J Physiol. 1966 Nov;187(1):195-200. doi: 10.1113/jphysiol.1966.sp008082.
Abstract
- The intestinal transport of D-xylose by sacs of everted small intestine of the hamster is partially inhibited by L-histidine in concentrations of 5, 10 and 20 mM but not of 2 mM.2. 20 mM concentrations of D-histidine and L-methionine also produce inhibition.3. The inhibition is not due to an alteration in water transport or to a change in pH of the incubating medium.4. The rate of the intestinal transport of L-xylose is about (1/4) of the rate of D-xylose transport and is unaffected by a 20 mM concentration of L-histidine.
摘要
- 仓鼠外翻小肠囊对D-木糖的肠道转运在L-组氨酸浓度为5、10和20 mM时受到部分抑制，但在2 mM时未受抑制。2. 20 mM浓度的D-组氨酸和L-蛋氨酸也会产生抑制作用。3. 这种抑制并非由于水转运的改变或孵育介质pH值的变化。4. L-木糖的肠道转运速率约为D-木糖转运速率的(1/4)，且不受20 mM浓度L-组氨酸的影响。
相似文献
1
The effect of amino acids on the intestinal transport of L- and D-xylose in vitro.氨基酸对L-木糖和D-木糖体外肠道转运的影响。
J Physiol. 1966 Nov;187(1):195-200. doi: 10.1113/jphysiol.1966.sp008082.
2
The use of dietary-restricted rat intestine for active transport studies.将饮食受限大鼠的肠道用于主动转运研究。
J Physiol. 1969 Nov;205(1):159-78. doi: 10.1113/jphysiol.1969.sp008958.
3
Effect of amino acids on sugar absorption.氨基酸对糖吸收的影响。
J Physiol. 1966 Sep;186(1):166-74. doi: 10.1113/jphysiol.1966.sp008026.
4
Effect of DL-ethionine on the intestinal absorption and transport of palmitic acid-1-14C and tripalmitin-14C. Role of intramucosal factors in the uptake of luminal lipids.DL-乙硫氨酸对棕榈酸-1-14C和三棕榈精-14C肠道吸收及转运的影响。黏膜内因子在肠腔脂质摄取中的作用。
J Clin Invest. 1969 Aug;48(8):1397-407. doi: 10.1172/JCI106105.
5
Role of exchange transport in the absorption of L-tryptophan in the small intestine of chicks.交换转运在雏鸡小肠中L-色氨酸吸收中的作用。
Comp Biochem Physiol A Comp Physiol. 1987;87(4):951-7. doi: 10.1016/0300-9629(87)90019-3.
6
Comparison of the effect of two different hypoglycemic agents, glibenclamide and HB 699, on the rat small intestinal absorption of sugars and amino acids.两种不同降糖药（格列本脲和HB 699）对大鼠小肠糖类和氨基酸吸收影响的比较。
Biochem Pharmacol. 1986 Sep 1;35(17):2929-35. doi: 10.1016/0006-2952(86)90488-0.
7
Studies on the competitive absorption of neutral L-amino acids from the avian small intestine.关于禽类小肠中中性L-氨基酸竞争性吸收的研究。
J Nutr. 1972 Dec;102(12):1563-7. doi: 10.1093/jn/102.12.1563.
8
Inhibition of intestinal sugar transport by phenformin.苯乙双胍对肠道糖转运的抑制作用。
Rev Esp Fisiol. 1975 Dec;31(4):251-4.
9
The effects of synthetic surfactants on intestinal permeability to glucose in vitro.合成表面活性剂对体外肠道葡萄糖通透性的影响。
Proc Soc Exp Biol Med. 1971 Sep;137(4):1135-9. doi: 10.3181/00379727-137-35742.
10
Effect of ethyl acetate on the transport of sodium and glucose in the hamster small intestine in vitro.乙酸乙酯对体外培养的仓鼠小肠中钠和葡萄糖转运的影响。
Biochim Biophys Acta. 1976 Mar 19;426(3):489-98. doi: 10.1016/0005-2736(76)90393-x.
引用本文的文献
1
The use of dietary-restricted rat intestine for active transport studies.将饮食受限大鼠的肠道用于主动转运研究。
J Physiol. 1969 Nov;205(1):159-78. doi: 10.1113/jphysiol.1969.sp008958.
2
[Absorption and malabsorption of protein digestion products].[蛋白质消化产物的吸收与吸收不良]
Klin Wochenschr. 1969 Apr 15;47(8):397-414. doi: 10.1007/BF01745784.
本文引用的文献
1
Absorption of amino acids from isolated surviving intestine.从离体存活肠道中吸收氨基酸。
Arch Biochem Biophys. 1955 Jun;56(2):424-40. doi: 10.1016/0003-9861(55)90263-0.
2
EFFECTS OF SUGARS ON INTESTINAL TRANSFER OF AMINO-ACIDS.糖类对氨基酸肠道转运的影响
Nature. 1964 Apr 25;202:400-1. doi: 10.1038/202400b0.
3
THE EFFECT OF PH ON THE ABSORPTION RATE OF GLUCOSE IN THE SMALL INTESTINE OF HUMANS.pH对人体小肠中葡萄糖吸收速率的影响
Gastroenterology. 1963 Aug;45:189-95.
4
Sac of everted intestine technic for study of intestinal absorption in vitro.外翻肠囊技术用于体外肠道吸收研究。
Methods Med Res. 1961;9:287-92.
5
Possible carrier mechanism for the intestinal transport of D-xylose.D-木糖肠道转运的可能载体机制。
Biochem Biophys Res Commun. 1961 Feb 24;4:123-6. doi: 10.1016/0006-291x(61)90360-6.
6
Studies on the mechanism of the intestinal absorption of sugars. III. Mutual inhibition, in vitro, between some actively transported sugars.糖类肠道吸收机制的研究。III. 某些主动转运糖类在体外的相互抑制作用。
Biochim Biophys Acta. 1960 Dec 18;45:477-82. doi: 10.1016/0006-3002(60)91483-9.
7
Ion and water fluxes in the ileum of rats.大鼠回肠中的离子和水通量
J Gen Physiol. 1957 Sep 20;41(1):143-68. doi: 10.1085/jgp.41.1.143.
8
The use of sacs of everted small intestine for the study of the transference of substances from the mucosal to the serosal surface.使用外翻小肠囊来研究物质从黏膜表面向浆膜表面的转运。
J Physiol. 1954 Jan;123(1):116-25. doi: 10.1113/jphysiol.1954.sp005036.
9
D-xylose active transport in the hamster small intestine.仓鼠小肠中的D-木糖主动转运
Biochim Biophys Acta. 1966 Feb 7;112(2):292-306. doi: 10.1016/0926-6585(66)90328-1.
10
Effect of amino acids on sugar absorption.氨基酸对糖吸收的影响。
J Physiol. 1966 Sep;186(1):166-74. doi: 10.1113/jphysiol.1966.sp008026.
Zotero 插件